{"pk":1050,"title":"Altered Mental Status in the Emergency Department – When to Consider Anti-LGI-1 Encephalitis: Case Report","subtitle":null,"abstract":"Introduction:\n Anti-leucine-rich glioma inactivated-1 (LGI-1) is one of few antibodies implicated in limbic encephalitis, a syndrome that can result in permanent neurological symptoms if left untreated.\nCase Report:\n We present a patient with dystonic seizures, progressive cognitive decline, psychiatric symptoms and short-term memory loss, and mild hyponatremia diagnosed with anti-LGI-1 antibody limbic encephalitis.\nConclusion:\n There are few reports in the emergency medicine community describing anti-LGI-1 antibody limbic encephalitis. Delay in diagnosis can risk irreversible limbic damage. Therefore, it is important for the emergency physician to be aware of anti-LGI-1 antibody limbic encephalitis when presented with adult-onset seizures and altered mental status of unknown etiology.","language":"en","license":{"name":"Creative Commons Attribution 4.0","short_name":"CC BY 4.0","text":"Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.","url":"https://creativecommons.org/licenses/by/4.0"},"keywords":[{"word":"Autoimmune encephalitis"},{"word":"altered mental status"},{"word":"LGI-1 antibody"},{"word":"limbic encephalitis"}],"section":"Case Reports","is_remote":true,"remote_url":"https://escholarship.org/uc/item/3xt6v5v1","frozenauthors":[{"first_name":"Stephanie","middle_name":"S.","last_name":"Miljkovic","name_suffix":"","institution":"Creighton University School of Medicine, Department of Emergency Medicine, Phoenix, Arizona","department":"None"},{"first_name":"B. Witkind","middle_name":"","last_name":"Koenig","name_suffix":"","institution":"Creighton University School of Medicine, Department of Emergency Medicine, Phoenix, Arizona","department":"None"}],"date_submitted":"2021-07-27T21:39:43+02:00","date_accepted":"2021-07-27T21:39:43+02:00","date_published":"2021-07-27T21:41:15+02:00","render_galley":null,"galleys":[{"label":"","type":"","path":"https://journalpub.escholarship.org/uciem_cpcem/article/1050/galley/792/download/"}]}