{"pk":11832,"title":"Challenging the One-Hour Sepsis Bundle","subtitle":null,"abstract":"In April 2018, the Surviving Sepsis Campaign (SSC) released an updated sepsis bundle, which combines directives previously listed in the three-hour and six-hour bundles. The authors discussed the reasoning and evidence supporting these changes. However, there are data that suggest these recommendations may be contrary to the best available evidence. Our purpose here is to highlight the areas where evidence is only as strong as the methodological constructs of the research used. This article is a narrative review of the available, limited evidence on which the one-hour bundle was based.","language":"en","license":{"name":"Creative Commons Attribution 4.0","short_name":"CC BY 4.0","text":"Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.","url":"https://creativecommons.org/licenses/by/4.0"},"keywords":[{"word":"sepsis, bundles, definitions"}],"section":"Endemic Infections","is_remote":true,"remote_url":"https://escholarship.org/uc/item/72w8j3fh","frozenauthors":[{"first_name":"Annahieta","middle_name":"","last_name":"Kalantari","name_suffix":"","institution":"Penn State Health Milton S. Hershey Medical Center, Department of Emergency Medicine, Hershey, Pennsylvania","department":"None"},{"first_name":"Salim","middle_name":"","last_name":"Rezaie","name_suffix":"","institution":"Greater San Antonio Emergency Physicians, Department of Emergency Medicine, San Antonio, Texas\nGreater San Antonio Emergency Physicians, Department of Internal Medicine, San Antonio, Texas","department":"None"}],"date_submitted":"2018-06-06T23:46:18Z","date_accepted":"2018-06-06T23:46:18Z","date_published":"2019-02-04T19:56:05Z","render_galley":null,"galleys":[{"label":"","type":"pdf","path":"https://journalpub.escholarship.org/westjem/article/11832/galley/6337/download/"}]}