Case Presentation: Early diagnosis and rapid treatment of cancer is essential for good clinical outcomes for patients. In this case, an 85-year-old man presented with failure to thrive and was noted to have rapid-onset, multiple seborrheic keratoses (Leser-Trélat sign) on his chest and back. He was ultimately diagnosed with pancreatic cancer using computed tomography.
Discussion: Leser-Trélat sign is a rare cutaneous marker for underlying malignancy. Identification of this sign can help guide diagnostic imaging and lab work to identify an occult internal malignancy, resulting in more rapid diagnosis, earlier treatment, and potentially better clinical outcomes.
","language":"eng","license":{"name":"Creative Commons Attribution 4.0","short_name":"CC BY 4.0","text":"Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.","url":"https://creativecommons.org/licenses/by/4.0"},"keywords":[{"word":"Leser-Trélat"},{"word":" cancer; malignancy; seborrheic keratosis"}],"section":"Images in Emergency Medicine","is_remote":true,"remote_url":"https://escholarship.org/uc/item/65n67683","frozenauthors":[{"first_name":"Kalpit","middle_name":"","last_name":"Modi","name_suffix":"","institution":"Einstein Healthcare Network, Einstein Medical Center Montgomery Emergency Department, East Norriton, Pennsylvania","department":""},{"first_name":"Richard","middle_name":"","last_name":"Chen","name_suffix":"","institution":"Einstein Healthcare Network, Einstein Medical Center Montgomery Emergency Department, East Norriton, Pennsylvania","department":""},{"first_name":"Layla","middle_name":"","last_name":"Abubshait","name_suffix":"","institution":"Einstein Healthcare Network, Einstein Medical Center Montgomery Emergency Department, East Norriton, Pennsylvania","department":""}],"date_submitted":"2023-03-27T06:20:51.678000Z","date_accepted":"2023-06-23T20:54:30.814000Z","date_published":"2023-08-14T16:00:00Z","render_galley":null,"galleys":[{"label":"PDF","type":"pdf","path":"https://journalpub.escholarship.org/uciem_cpcem/article/1248/galley/1147/download/"}]}