{"pk":16616,"title":"Fatal Metformin Overdose Presenting with Progressive Hyperglycemia","subtitle":null,"abstract":"A 29-year-old man with no history of diabetes ingested over 60 grams of metformin in a suicide attempt. He presented to the emergency department with acute renal insufficiency, severe lactic acidosis, and rapidly-progressive hyperglycemia. The patient’s peak serum glucose level of 707 mg/dL is the highest yet reported in a case of metformin toxicity. Treatment included sodium bicarbonate infusion and hemodialysis, but the patient suffered several cardiac arrests with pulseless electrical activity and ultimately expired 25 hours after the ingestion.\n\n\n[WestJEM. 2008;9:160-164.]","language":"en","license":{"name":"none","short_name":"none","text":"","url":"http://google.com"},"keywords":[{"word":"overdose"},{"word":"poisoning"},{"word":"Metformin"},{"word":"hyperglycemia"},{"word":"lactic acidosis"}],"section":"Article","is_remote":true,"remote_url":"https://escholarship.org/uc/item/1nh2f6wn","frozenauthors":[{"first_name":"Jeffrey","middle_name":"R","last_name":"Suchard","name_suffix":"","institution":"Department of Emergency Medicine, University of California, Irvine School of Medicine","department":"None"},{"first_name":"Thomas","middle_name":"A","last_name":"Grotsky","name_suffix":"","institution":"Department of Emergency Medicine, University of California, Irvine School of Medicine","department":"None"}],"date_submitted":"2008-02-19T08:00:00Z","date_accepted":"2008-02-19T08:00:00Z","date_published":"2008-06-23T07:00:00Z","render_galley":null,"galleys":[{"label":"","type":"pdf","path":"https://journalpub.escholarship.org/westjem/article/16616/galley/8407/download/"}]}