{"pk":17126,"title":"Lidocaine Toxicity Misinterpreted as a Stroke","subtitle":null,"abstract":"For more than 50 years lidocaine has been used to treat ventricular arrhythmias. Neurologic dysfunction, manifested as a stroke, occurred acutely in an 87-year-old woman after she had been administered repeated doses of lidocaine, a lidocaine infusion, then an intravenous amiodarone infusion for ventricular tachycardia. This was ultimately diagnosed as lidocaine toxicity with a serum lidocaine level of 7.9 mg/L (1.5 - 6.0 mg/L). We discuss lidocaine toxicity and risk factors leading to its development, which include particularly hepatic dysfunction, cardiac dysfunction, advanced age and other drug administration.\n\n\n[West J Emerg Med. 2009;10(4):292-294.]","language":"en","license":{"name":"none","short_name":"none","text":"","url":"http://google.com"},"keywords":[{"word":"Lidocaine"},{"word":"drug toxicity"},{"word":"stroke"},{"word":"Emergency Medicine"}],"section":"Article","is_remote":true,"remote_url":"https://escholarship.org/uc/item/6b31j01f","frozenauthors":[{"first_name":"Benjamin","middle_name":"","last_name":"Bursell","name_suffix":"","institution":"University of CT Combined Residency in EM","department":"None"},{"first_name":"Alan","middle_name":"J","last_name":"Smally","name_suffix":"","institution":"University of Connecticut School of Medicine and Dentistry","department":"None"},{"first_name":"Richard","middle_name":"M","last_name":"Ratzan","name_suffix":"","institution":"University of CT School of Medicine and Dentistry","department":"None"}],"date_submitted":"2008-05-25T07:00:00Z","date_accepted":"2008-05-25T07:00:00Z","date_published":"2009-11-01T07:00:00Z","render_galley":null,"galleys":[{"label":"","type":"pdf","path":"https://journalpub.escholarship.org/westjem/article/17126/galley/8652/download/"}]}