{"pk":17433,"title":"Cocaine-Associated Seizures and Incidence of Status Epilepticus","subtitle":null,"abstract":"Objectives: Acute complications from cocaine abuse are commonly treated in the emergency department (ED); one of the most consequential is status epilepticus. The incidence of this complication is not clearly defined in the prior literature on cocaine-associated sequelae. We evaluated the incidence of status epilepticus in patients with seizures secondary to suspected cocaine use.\n\n\nMethods: We performed a retrospective multi-center study of patients with seizures resulting from cocaine use. We identified study subjects at 15 hospitals by record review and conducted a computer-assisted records search to identify patients with seizures for each institution over a four-year period. We selected subjects from this group on the basis of cocaine use and determined the occurrence of status epilepticus among them. Data were collected on each subject using a standardized data collection form.\n\n\nResults: We evaluated 43 patients in the ED for cocaine-associated seizures. Their age range was 17 to 54, with a mean age was 31 years; 53% were male. Of 43 patients, 42 experienced a single tonic-clonic seizure and one developed status epilepticus. All patients had either a history of cocaine use or positive urine drug screen for cocaine.\n\n\nConclusion: Despite reported cases of status epilepticus with cocaine-induced seizures, the incidence of this complication was unclear based on prior literature. This study shows that most cocaine-associated seizures are self-limited. [West J Emerg Med. 2010; 11(2):157-160.]","language":"en","license":{"name":"Creative Commons Attribution-NonCommercial  4.0","short_name":"CC BY-NC 4.0","text":"Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNonCommercial — You may not use the material for commercial purposes.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.","url":"https://creativecommons.org/licenses/by-nc/4.0"},"keywords":[{"word":"Cocaine"},{"word":"seizures"},{"word":"status epilepticus"},{"word":"cocaine-associated seizures"},{"word":"toxin"},{"word":"Emergency Medicine"},{"word":"Medicine"}],"section":"Article","is_remote":true,"remote_url":"https://escholarship.org/uc/item/0nm7d20d","frozenauthors":[{"first_name":"Nima","middle_name":"","last_name":"Majlesi","name_suffix":"","institution":"Morristown Memorial Hospital, Department of Emergency Medicine, Morristown, NJ","department":"None"},{"first_name":"Richard","middle_name":"D","last_name":"Shih","name_suffix":"","institution":"Morristown Memorial Hospital, Department of Emergency Medicine, Morristown, NJ","department":"None"},{"first_name":"Frederick","middle_name":"W","last_name":"Fiesseler","name_suffix":"","institution":"Morristown Memorial Hospital, Department of Emergency Medicine, Morristown, NJ","department":"None"},{"first_name":"Oliver","middle_name":"","last_name":"Hung","name_suffix":"","institution":"Morristown Memorial Hospital, Department of Emergency Medicine, Morristown, NJ","department":"None"},{"first_name":"Renato","middle_name":"R.","last_name":"Debellonia","name_suffix":"","institution":"New Jersy Poison Center, Newark, NJ","department":"None"}],"date_submitted":"2009-07-24T07:00:00Z","date_accepted":"2009-07-24T07:00:00Z","date_published":"2010-07-28T07:00:00Z","render_galley":null,"galleys":[{"label":"","type":"pdf","path":"https://journalpub.escholarship.org/westjem/article/17433/galley/8873/download/"}]}