{"pk":19412,"title":"ST-Elevation Myocardial Infarction Due to Coronary Vasospasm Associated with Eosinophilic Granulomatosis with Polyangiitis: A Case Report","subtitle":null,"abstract":"<p><strong>Introduction:</strong> ST-elevation myocardial infarction (STEMI) can be caused by underlying coronary artery vasospasm (CAV) with or without associated atherosclerotic disease. Coronary artery vasospasm is a rare but potentially devastating manifestation of eosinophilic granulomatosis with polyangiitis (EGPA).</p>\n<p><br><strong>Case Report:</strong> We describe a 54-year-old male with a known history of EGPA and coronary artery disease presenting to the emergency department with chest pain and an inferior STEMI on electrocardiogram. He was ultimately taken for coronary angiography and found to have a discrete vasospastic lesion in the right coronary artery that was treated with intra-coronary nitroglycerin and calcium channel blockers. He was continued on immunosuppressant agents (prednisone and mepolizumab) for management of EGPA and followed up with outpatient cardiology and rheumatology for vasospastic angina.</p>\n<p><br><strong>Conclusion:</strong> This case highlights a rare cause of STEMI, discusses the nuances in treatment of STEMI due to CAV, and provides background on pathophysiology and treatment of EGPA.</p>","language":"eng","license":{"name":"Creative Commons Attribution 4.0","short_name":"CC BY 4.0","text":"Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.","url":"https://creativecommons.org/licenses/by/4.0"},"keywords":[{"word":"case report"},{"word":"STEMI"},{"word":"coronary artery vasospasm"},{"word":"eosinophilic granulomatosis with polyangiitis"}],"section":"Case Reports","is_remote":true,"remote_url":"https://escholarship.org/uc/item/4hc160x8","frozenauthors":[{"first_name":"Christopher","middle_name":"","last_name":"Allen","name_suffix":"","institution":"Mayo Clinic Alix School of Medicine, Scottsdale, Arizona","department":""},{"first_name":"Christopher","middle_name":"","last_name":"Poyorena","name_suffix":"","institution":"Mayo Clinic Alix School of Medicine, Scottsdale, Arizona","department":""},{"first_name":"Lauren","middle_name":"B.","last_name":"Querin","name_suffix":"","institution":"Mayo Clinic Hospital Phoenix, Department of Emergency Medicine, Phoenix, Arizona","department":""}],"date_submitted":"2024-02-08T02:38:25.103000Z","date_accepted":"2024-03-12T05:12:33.907000Z","date_published":"2024-06-14T13:00:00Z","render_galley":{"label":"Final Article","type":"pdf","path":"https://journalpub.escholarship.org/uciem_cpcem/article/19412/galley/14448/download/"},"galleys":[{"label":"Layout","type":"pdf","path":"https://journalpub.escholarship.org/uciem_cpcem/article/19412/galley/10839/download/"},{"label":"Final Article","type":"pdf","path":"https://journalpub.escholarship.org/uciem_cpcem/article/19412/galley/14448/download/"}]}