{"pk":24789,"title":"Neural lateralization during number line estimation differentially predicts numerical and spatial capacity","subtitle":null,"abstract":"Numerical and spatial skills are highly interrelated, and both contribute to mathematical cognition. Spatial-numerical associations are frequently examined using number line estimation (NLE); however, there is considerable debate about the relative contributions of number-specific and domain-general (i.e., working memory) processing involved in this task. Here, we used functional neuroimaging to examine the processes supporting NLE in adults (n = 47). Participants completed an in-scanner NLE task and number localizer. We found that within left and right parietal number regions, neural activity during the in-scanner NLE task differentially predicted out-of-scanner behavioral measures. Specifically, activity in the left (but not right) posterior intraparietal sulcus (IPS) predicted visuo-spatial working memory, and activity in the left (but not right) anterior IPS predicted performance on an out-of-scanner NLE task. These findings suggest that NLE relies on both spatial-numerical and domain-general capacities supported by left-hemisphere parietal regions, challenging hypotheses about right-lateralized visuo-spatial contributions to number processing.","language":"eng","license":{"name":"","short_name":"","text":null,"url":""},"keywords":[{"word":"Cognitive Neuroscience; Spatial cognition; fMRI"}],"section":"Abstracts","is_remote":true,"remote_url":"https://escholarship.org/uc/item/19z9b9pk","frozenauthors":[{"first_name":"Caroline","middle_name":"","last_name":"Kaicher","name_suffix":"","institution":"Carnegie Mellon University","department":""},{"first_name":"Lauren","middle_name":"","last_name":"Aulet","name_suffix":"","institution":"Carnegie Mellon University","department":""},{"first_name":"Jessica","middle_name":"","last_name":"Cantlon","name_suffix":"","institution":"Carnegie Mellon University","department":""}],"date_submitted":null,"date_accepted":null,"date_published":"2024-01-01T10:00:00-08:00","render_galley":{"label":"PDF","type":"pdf","path":"https://journalpub.escholarship.org/cognitivesciencesociety/article/24789/galley/21403/download/"},"galleys":[{"label":"PDF","type":"pdf","path":"https://journalpub.escholarship.org/cognitivesciencesociety/article/24789/galley/14387/download/"},{"label":"PDF","type":"pdf","path":"https://journalpub.escholarship.org/cognitivesciencesociety/article/24789/galley/18244/download/"},{"label":"PDF","type":"pdf","path":"https://journalpub.escholarship.org/cognitivesciencesociety/article/24789/galley/21403/download/"}]}