{"pk":29379,"title":"Prefrontal-striatal circuitry supportsadaptive memory prioritization across development","subtitle":null,"abstract":"Previous work has revealed that the ability to strategically en-code high-value information may improve gradually over de-velopment as cognitive control mechanisms mature. However,studies of value-directed memory have relied on explicit cuesof information value, which are rarely present in real-worldcontexts. Here, using a novel fMRI paradigm, we examinedwhether individuals across a wide age range (N = 90; ages 8– 25 years) could learn the value of information from expe-rience and use learned value signals to strategically modulatememory. We found that memory prioritization for high-valueinformation improved across development, and was supportedby increased engagement of the caudate and prefrontal cortexduring both encoding and retrieval of high-value information.Our results suggest that across development, the dynamic ad-justment of memory based on the statistics of the environmentis supported by a wide network of brain regions involved inboth the recognition and use of information value.","language":"eng","license":{"name":"","short_name":"","text":null,"url":""},"keywords":[{"word":"motivated memory; cognitive development;fMRI"}],"section":"Memory","is_remote":true,"remote_url":"https://escholarship.org/uc/item/4t5836f5","frozenauthors":[{"first_name":"Kate","middle_name":"","last_name":"Nussenbaum","name_suffix":"","institution":"New York University","department":""},{"first_name":"Catherine","middle_name":"A.","last_name":"Hartley","name_suffix":"","institution":"New York University","department":""}],"date_submitted":null,"date_accepted":null,"date_published":"2020-01-01T18:00:00Z","render_galley":null,"galleys":[{"label":"PDF","type":"pdf","path":"https://journalpub.escholarship.org/cognitivesciencesociety/article/29379/galley/19240/download/"}]}