{"pk":43494,"title":"Intravenous Low-Dose Buprenorphine for Acute Pain Management in the Emergency Department: A Case Series ","subtitle":null,"abstract":"<p><strong>Introduction</strong>: Buprenorphine is used for treating opioid use disorder, but its role as an analgesic in the emergency department (ED) is frequently overlooked. Emerging evidence indicates that, at low doses, it can be used safely and advantageously as an alternative to full-agonist opioids for treating acute pain.</p>\n<p><strong>Case Series: </strong>This case series examines the novel use of intravenous (IV) low-dose buprenorphine for acute pain management in the ED for five patients presenting with diverse past medical history and varied painful indications.</p>\n<p><strong>Conclusion: </strong>Intravenous low-dose buprenorphine may represent an important new tool in our ED armamentarium, and research into its role in emergency pain management is warranted. Further work is needed to determine optimal dosing strategies and identify which patients will be most likely to benefit from IV low-dosebuprenorphine in the ED.</p>","language":"eng","license":{"name":"Creative Commons Attribution 4.0","short_name":"CC BY 4.0","text":"Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.","url":"https://creativecommons.org/licenses/by/4.0"},"keywords":[{"word":"buprenorphine"},{"word":"acute pain"},{"word":"Analgesia"},{"word":"Opioids"}],"section":"Case Series","is_remote":true,"remote_url":"https://escholarship.org/uc/item/3x35f05c","frozenauthors":[{"first_name":"Jonathan","middle_name":"Bryan","last_name":"Lee","name_suffix":"","institution":"Stanford University School of Medicine, Department of Anesthesiology, Perioperative, and Pain Medicine, Palo Alto, California; Stanford University School of Medicine, Department of Emergency Medicine, Palo Alto, California","department":""},{"first_name":"Nicholas","middle_name":"Geoffrey","last_name":"Ashenburg","name_suffix":"","institution":"Stanford University School of Medicine, Department of Emergency Medicine, Palo Alto, California","department":""},{"first_name":"Joshua","middle_name":"","last_name":"Park","name_suffix":"","institution":"Stanford Health Care, Department of Pharmacy, Palo Alto, California","department":""},{"first_name":"Terence","middle_name":"","last_name":"Ahern","name_suffix":"","institution":"Stanford University School of Medicine, Department of Emergency Medicine, Palo Alto, California","department":""}],"date_submitted":"2025-02-13T07:44:24.346000+06:00","date_accepted":"2025-04-12T00:15:42.444000+06:00","date_published":"2025-07-15T10:04:00+06:00","render_galley":null,"galleys":[{"label":"PDF","type":"pdf","path":"https://journalpub.escholarship.org/uciem_cpcem/article/43494/galley/38473/download/"}]}