{"pk":43503,"title":"The Trigeminocardiac Reflex? Severe Bradycardia Secondary to Facial Trauma: A Case Report","subtitle":null,"abstract":"<p><strong>Introduction</strong>: The trigeminocardiac reflex (TCR), a physiologic response to irritation of the branches of the trigeminal nerve, was first described in humans in 1870. Gastric hypermobility, hypotension, bradycardia, and even asystole have been reported in response to surgical manipulation of the trigeminal nerve and its branches, but literature is limited in patients not undergoing surgery. Although effects are generally transient and benign, TCR can present a significant diagnostic and therapeutic challenge in patients undergoing surgical manipulation of the trigeminal nerve and its branches.</p>\n<p><strong>Case Report</strong>: We describe a case of severe bradycardia secondary to facial trauma causing hemodynamic compromise and diagnostic uncertainty.</p>\n<p><strong>Conclusion</strong>: This case highlights a possible case of TCR, as well as therapeutic considerations, in a patient presenting to the emergency department with severe facial trauma.</p>","language":null,"license":{"name":"Creative Commons Attribution 4.0","short_name":"CC BY 4.0","text":"Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.","url":"https://creativecommons.org/licenses/by/4.0"},"keywords":[{"word":"case report"},{"word":"trigeminocardiac reflex"},{"word":"facial trauma"},{"word":"bradycardia"}],"section":"Case Reports","is_remote":true,"remote_url":"https://escholarship.org/uc/item/97k585gq","frozenauthors":[{"first_name":"Boris","middle_name":"","last_name":"Penev","name_suffix":"","institution":"Medical University of South Carolina, Department of Emergency Medicine, Charleston, South Carolina","department":""},{"first_name":"Hallmon","middle_name":"","last_name":"Hughes","name_suffix":"","institution":"Medical University of South Carolina, College of Medicine, Charleston, South Carolina","department":""},{"first_name":"Katherine","middle_name":"","last_name":"Scarpino","name_suffix":"","institution":"Medical University of South Carolina, Department of Emergency Medicine, Charleston, South Carolina","department":""},{"first_name":"Daniel","middle_name":"","last_name":"Ritter","name_suffix":"","institution":"Medical University of South Carolina, Department of Emergency Medicine, Charleston, South Carolina","department":""}],"date_submitted":"2025-02-13T20:05:42.327000Z","date_accepted":"2025-05-09T07:08:57.332000Z","date_published":"2025-07-09T06:50:00Z","render_galley":null,"galleys":[{"label":"PDF","type":"pdf","path":"https://journalpub.escholarship.org/uciem_cpcem/article/43503/galley/38486/download/"}]}