{"pk":58975,"title":"Effects of Consuming Dietary Fructose versus Glucose on de novo Lipogenesis in Overweight and Obese Human Subjects","subtitle":null,"abstract":"The effects of consuming a diet high in fructose,compared to a diet high in glucose, on the rate ofhepatic de novo lipogenesis (DNL) in overweightand obese individuals were studied. Thesesubjects were given a diet in which either glucoseor fructose was substituted for 25% of their energyrequirements for 10 weeks. During the fasted state,subjects’ DNL for those on a glucose and fructosediet were similar. However, in the fed state, DNLwas increased significantly in subjects given afructose diet. This suggests that consuming adiet from fructose-sweetened beverages increases DNL.","language":"en","license":null,"keywords":[{"word":"High fructose diet, DNL, de novo lipogenesis"},{"word":"Public Health, Biology, Molecular Biology, Metabolism, Molecular Biology, Cell Biology"}],"section":"Research","is_remote":true,"remote_url":"https://escholarship.org/uc/item/7vv7z7zw","frozenauthors":[{"first_name":"Patrick","middle_name":"","last_name":"Lam","name_suffix":"","institution":"UC Berkeley","department":""}],"date_submitted":"2011-12-15T02:23:42Z","date_accepted":"2011-12-15T02:23:42Z","date_published":"2011-12-15T02:24:04Z","render_galley":null,"galleys":[{"label":"","type":"pdf","path":"https://journalpub.escholarship.org/our_bsj/article/58975/galley/45020/download/"}]}