{"pk":6609,"title":"The Rare Sore Throat: A Case of Thyroid Storm and Agranulocytosis","subtitle":null,"abstract":"Introduction: Thyroid storm is a rare but potentially life-threatening metabolic disorder that presents unique management challenges in the emergency department. Thionamides are commonly used as monotherapy for first-line treatment of hyperthyroidism.

Case Report: In this case, a 26-year-old male presented to the emergency department with sore throat, fever, and diarrhea. He was found to have thyrotoxicosis as well as methimazole-induced bone marrow suppression resulting in agranulocytosis.

Conclusion: Thyroid storm is a rare condition that carries a high risk of mortality and can further compromise a patient’s immune system due to complications of common treatment modalities. It can potentially be misdiagnosed as sepsis due to tachycardia, febrile state, and tachypnea. This case report includes a discussion of diagnostic studies, as well as medical and surgical treatment modalities that led to the patient’s recovery.

","language":"eng","license":{"name":"Creative Commons Attribution 4.0","short_name":"CC BY 4.0","text":"Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.","url":"https://creativecommons.org/licenses/by/4.0"},"keywords":[{"word":"case report"},{"word":"thyrotoxicosis"},{"word":"methimazole"},{"word":"bone marrow suppression"},{"word":"agranulocytosis"}],"section":"Case Reports","is_remote":true,"remote_url":"https://escholarship.org/uc/item/1251v3fc","frozenauthors":[{"first_name":"Matthew","middle_name":"J.","last_name":"Kunz","name_suffix":"","institution":"Creighton of Phoenix Arizona (COPA), Emergency Medicine, Phoenix, Arizona","department":""},{"first_name":"Wayne","middle_name":"A.","last_name":"Martini","name_suffix":"","institution":"Mayo Clinic, Department of Emergency Medicine, Phoenix, Arizona","department":""},{"first_name":"Levi","middle_name":"","last_name":"Filler","name_suffix":"","institution":"University of Arizona College of Medicine - Phoenix, Department of Emergency Medicine, Phoenix, Arizona","department":""}],"date_submitted":"2023-12-06T20:49:15.532000Z","date_accepted":"2023-12-06T20:53:51.432000Z","date_published":"2023-12-06T14:00:00Z","render_galley":{"label":"Final Article","type":"pdf","path":"https://journalpub.escholarship.org/uciem_cpcem/article/6609/galley/3844/download/"},"galleys":[{"label":"Final Article","type":"pdf","path":"https://journalpub.escholarship.org/uciem_cpcem/article/6609/galley/3844/download/"}]}