{"pk":718,"title":"Acute Toxin-Mediated Rhabdomyolysis During Treatment ith Trimethoprim-Sulfamethoxazole","subtitle":null,"abstract":"Rhabdomyolysis is a condition in which skeletal muscle breakdown causes the release of intracellular components into the bloodstream – defined as elevations in serum creatine kinase levels. The etiology of rhabdomyolysis is varied and may be the result of toxin-mediated mechanisms or metabolic derangements, or they may develop secondary to other conditions such as seizures, trauma and prolonged immobilization. In this case, we present a patient with suspected acute toxin-mediated rhabdomyolysis in the setting of trimethoprim-sulfamethoxazole (TMP-SMX) therapy for urinary tract infection. To our knowledge, this marks the fifth case report of an otherwise healthy patient diagnosed with rhabdomyolysis thought to be secondary to TMP-SMX.","language":"en","license":{"name":"Creative Commons Attribution 4.0","short_name":"CC BY 4.0","text":"Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.","url":"https://creativecommons.org/licenses/by/4.0"},"keywords":[],"section":"Case Reports","is_remote":true,"remote_url":"https://escholarship.org/uc/item/9fd334vk","frozenauthors":[{"first_name":"Michael","middle_name":"","last_name":"Sperandeo","name_suffix":"","institution":"Northwell Health at North Shore University Hospital, Department of Emergency Medicine, Manhasset, New York; Northwell Health at Long Island Jewish Medical Center, Department of Emergency Medicine, New Hyde Park, New York; Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York","department":"None"},{"first_name":"Dorjan","middle_name":"","last_name":"Pantic","name_suffix":"","institution":"Northwell Health at North Shore University Hospital, Department of Emergency Medicine, Manhasset, New York; Northwell Health at Long Island Jewish Medical Center, Department of Emergency Medicine, New Hyde Park, New York; Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York","department":"None"},{"first_name":"Jessica","middle_name":"","last_name":"Army","name_suffix":"","institution":"Northwell Health at North Shore University Hospital, Department of Emergency Medicine, Manhasset, New York; Northwell Health at Long Island Jewish Medical Center, Department of Emergency Medicine, New Hyde Park, New York; Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York","department":"None"}],"date_submitted":"2019-09-23T22:36:25+03:00","date_accepted":"2019-09-23T22:36:25+03:00","date_published":"2019-09-23T10:00:00+03:00","render_galley":null,"galleys":[{"label":"","type":"","path":"https://journalpub.escholarship.org/uciem_cpcem/article/718/galley/473/download/"}]}