{"pk":729,"title":"Pennies for Your Thoughts: A Case Series of Pancytopenia Due to Zinc-Induced Copper Deficiency in the Same Patient","subtitle":null,"abstract":"A 47-year-old schizophrenic male presented on three separate occasions with pancytopenia and sideroblastic anemia due to copper deficiency from massive zinc penny ingestion. The poisoning was treated differently on each visit: intravenous (IV) copper plus surgical decontamination and chelation with calcium disodium versenate (CaNa2EDTA); IV copper plus whole bowel irrigation; and IV copper with surgical decontamination only. Serum zinc half-lives were 80.0 hours, 233.2 hours, and 83.9 hours, respectively. Importantly, chelation with CaNa2EDTA did not significantly alter the elimination half-life. This is the first reported case of the same patient being treated on three different occasions with three different regimens for this condition.","language":"en","license":{"name":"Creative Commons Attribution 4.0","short_name":"CC BY 4.0","text":"Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.","url":"https://creativecommons.org/licenses/by/4.0"},"keywords":[],"section":"Case Series","is_remote":true,"remote_url":"https://escholarship.org/uc/item/5956p39r","frozenauthors":[{"first_name":"Bram","middle_name":"A.","last_name":"Dolcourt","name_suffix":"","institution":"Wayne State University, Department of Emergency Medicine, Detroit, Michigan","department":"None"},{"first_name":"James","middle_name":"H.","last_name":"Paxton","name_suffix":"","institution":"Wayne State University, Department of Emergency Medicine, Detroit, Michigan","department":"None"},{"first_name":"Keenan","middle_name":"M.","last_name":"Bora","name_suffix":"","institution":"Wayne State University, Department of Emergency Medicine, Detroit, Michigan","department":"None"},{"first_name":"Cynthia","middle_name":"K.","last_name":"Aaron","name_suffix":"","institution":"Wayne State University, Department of Emergency Medicine, Detroit, Michigan","department":"None"}],"date_submitted":"2019-10-15T00:41:47Z","date_accepted":"2019-10-15T00:41:47Z","date_published":"2019-10-15T00:52:24Z","render_galley":null,"galleys":[{"label":"","type":"","path":"https://journalpub.escholarship.org/uciem_cpcem/article/729/galley/484/download/"}]}