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{
    "pk": 1000,
    "title": "Nebulized Tranexamic Acid for Pediatric Post-tonsillectomy Hemorrhage: A Report of Two Cases",
    "subtitle": null,
    "abstract": "Introduction:\n Tranexamic acid (TXA) use in pediatrics to control hemorrhage has gained interest in recent years, but there is limited literature on nebulized TXA especially regarding dosing and adverse effects. Tranexamic acid has anti-fibrinolytic properties via competitive inhibition of plasminogen activation making it a logical approach to promote hemostasis in cases of post-tonsillectomy hemorrhage.\nCase Report:\n We describe two cases of post-tonsillectomy hemorrhage managed with nebulized TXA. In both cases, bleeding was stopped after TXA administration.\nConclusion:\n To our knowledge, this is the first case report to describe the use of nebulized TXA without an adjunct pharmacotherapy. Our two cases add additional reportable data on the safety of nebulized TXA and possible effectiveness on post-tonsillectomy hemorrhage.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "post-tonsillectomy hemorrhage"
        },
        {
            "word": "nebulized tranexamic acid"
        },
        {
            "word": "tranexamic acid"
        }
    ],
    "section": "Case Reports",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/1rm0g425",
    "frozenauthors": [
        {
            "first_name": "Cecilia",
            "middle_name": "",
            "last_name": "Monteilh",
            "name_suffix": "",
            "institution": "Phoenix Children’s Hospital, Department of Emergency Medicine, Phoenix, Arizona",
            "department": "None"
        },
        {
            "first_name": "Lydia",
            "middle_name": "",
            "last_name": "Rabon",
            "name_suffix": "",
            "institution": "Phoenix Children’s Hospital, Department of Emergency Medicine, Phoenix, Arizona",
            "department": "None"
        },
        {
            "first_name": "Ilana",
            "middle_name": "",
            "last_name": "Mayer-Hirshfeld",
            "name_suffix": "",
            "institution": "Valleywise Health Medical Center, Department of Emergency Medicine, Phoenix, Arizona",
            "department": "None"
        },
        {
            "first_name": "Jon",
            "middle_name": "",
            "last_name": "McGreevy",
            "name_suffix": "",
            "institution": "Phoenix Children’s Hospital, Department of Emergency Medicine, Phoenix, Arizona",
            "department": "None"
        }
    ],
    "date_submitted": "2021-03-13T12:15:55+08:00",
    "date_accepted": "2021-03-13T12:15:55+08:00",
    "date_published": "2021-03-13T12:17:30+08:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "",
            "path": "https://journalpub.escholarship.org/uciem_cpcem/article/1000/galley/747/download/"
        }
    ]
}