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{
    "pk": 1007,
    "title": "A Report of Two Cases: Unlearning Lactic Acidosis",
    "subtitle": null,
    "abstract": "Introduction:\n The term “lactic acidosis” reinforces the misconception that lactate contributes to acidemia. Although it is common to discover an anion gap acidosis with a concomitant elevated lactate concentration, the two are not mutually dependent.\nCase Report:\n Here we describe two patients exhibiting high lactate concentrations in the setting of metabolic alkalemia.\nConclusion:\n Lactate is not necessarily the direct cause of acid-base disturbances, and there is no fixed relationship between lactate and the anion gap or between lactate and pH. The term “metabolic acidosis with hyperlactatemia” is more specific than “lactic acidosis” and thus more appropriate.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "lactate"
        },
        {
            "word": "anion gap"
        },
        {
            "word": "acidosis"
        },
        {
            "word": "alkalosis"
        }
    ],
    "section": "Case Reports",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/64h7s607",
    "frozenauthors": [
        {
            "first_name": "Sanjay",
            "middle_name": "",
            "last_name": "Mohan",
            "name_suffix": "",
            "institution": "NYU Grossman School of Medicine, Ronald O. Perelman Department of Emergency Medicine, New York, New York",
            "department": "None"
        },
        {
            "first_name": "David",
            "middle_name": "S.",
            "last_name": "Goldfarb",
            "name_suffix": "",
            "institution": "NYU Grossman School of Medicine, Division of Nephrology, New York, New York",
            "department": "None"
        },
        {
            "first_name": "Robert",
            "middle_name": "S.",
            "last_name": "Hoffman",
            "name_suffix": "",
            "institution": "NYU Grossman School of Medicine, Ronald O. Perelman Department of Emergency Medicine, New York, New York",
            "department": "None"
        }
    ],
    "date_submitted": "2021-04-08T16:19:21-04:00",
    "date_accepted": "2021-04-08T16:19:21-04:00",
    "date_published": "2021-04-08T16:21:50-04:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "",
            "path": "https://journalpub.escholarship.org/uciem_cpcem/article/1007/galley/754/download/"
        }
    ]
}