Article Instance

HTTP 200 OK
Allow: GET
Content-Type: application/json
Vary: Accept

{
    "pk": 1064,
    "title": "Case Report: An Intracranial Complication of COVID-19 Nasopharyngeal Swab",
    "subtitle": null,
    "abstract": "Introduction:\n Cerebrospinal fluid (CSF) leaks are often the result of trauma or recent surgical procedures; however, a subset can develop from non-traumatic etiologies. Cerebrospinal fluid leaks from congenital and spontaneous encephaloceles can be clinically occult and have devastating consequences if undetected for prolonged periods of time. This report highlights a unique case of meningitis after CSF leak caused by ruptured congenital meningocele during a routine nasopharyngeal swab.\nCase Report:\n A 54-year-old female with diagnosed CSF leak presented to the emergency department (ED) with acute onset of severe headache, and neck and back pain. Prior to this presentation, the patient had experienced two months of persistent headache and rhinorrhea since her coronavirus disease 2019 (COVID-19) nasopharyngeal swab. As part of her outpatient workup, an otolaryngology consultation with subsequent beta-2 transferrin testing and magnetic resonance imaging was performed and she was diagnosed with a CSF leak from ruptured congenital meningocele. On ED presentation, she was afebrile, but with mild tachycardia, leukocytosis, and meningismus. Lumbar puncture revealed acute streptococcal meningitis. This patient’s meningitis developed due to prolonged occult CSF leak after her COVID-19 nasopharyngeal swab ruptured a pre-existing congenital meningocele.\nConclusion:\n Nasopharyngeal swabs are being performed much more frequently due to the COVID-19 pandemic. All front-line providers should be aware of the potential presence and rupture of congenital meningoceles in patients who have undergone recent nasopharyngeal swab when risk-stratifying for potential CSF leak and meningitis.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "nasopharyngeal swab"
        },
        {
            "word": "meningitis"
        },
        {
            "word": "cerebrospinal fluid leak"
        },
        {
            "word": "meningocele"
        },
        {
            "word": "encephalocele."
        }
    ],
    "section": "Case Reports",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/5vw2q86v",
    "frozenauthors": [
        {
            "first_name": "Alexandria",
            "middle_name": "",
            "last_name": "Holmes",
            "name_suffix": "",
            "institution": "Carolinas Medical Center, Department of Emergency Medicine, Charlotte, North Carolina",
            "department": "None"
        },
        {
            "first_name": "Bryant",
            "middle_name": "",
            "last_name": "Allen",
            "name_suffix": "",
            "institution": "Carolinas Medical Center, Department of Emergency Medicine, Charlotte, North Carolina",
            "department": "None"
        }
    ],
    "date_submitted": "2021-08-05T05:32:34Z",
    "date_accepted": "2021-08-05T05:32:34Z",
    "date_published": "2021-08-05T05:38:23Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "",
            "path": "https://journalpub.escholarship.org/uciem_cpcem/article/1064/galley/806/download/"
        }
    ]
}