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{
    "pk": 11058,
    "title": "Comparing Quick Sequential Organ Failure Assessment Scores to End-tidal Carbon Dioxide as Mortality Predictors in Prehospital Patients with Suspected Sepsis",
    "subtitle": null,
    "abstract": "Introduction: \nEarly identification of sepsis significantly improves outcomes, suggesting a role for prehospital screening. An end-tidal carbon dioxide (ETCO2) value ≤ 25 mmHg predicts mortality and severe sepsis when used as part of a prehospital screening tool. Recently, the Quick Sequential Organ Failure Assessment (qSOFA) score was also derived as a tool for predicting poor outcomes in potentially septic patients. \n \nMethods:\n We conducted a retrospective cohort study among patients transported by emergency medical services to compare the use of ETCO2 ≤ 25 mmHg with qSOFA score of ≥ 2 as a predictor of mortality or diagnosis of severe sepsis in prehospital patients with suspected sepsis. \nResults:\n By comparison of receiver operator characteristic curves, ETCO2 had a higher discriminatory power to predict mortality, sepsis, and severe sepsis than qSOFA. \nConclusion:\n Both non-invasive measures were easily obtainable by prehospital personnel, with ETCO2 performing slightly better as an outcome predictor.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "qSOFA, ETCO2, sepsis, prehospital"
        }
    ],
    "section": "Endemic Infections",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/13t079pw",
    "frozenauthors": [
        {
            "first_name": "Christopher",
            "middle_name": "L.",
            "last_name": "Hunter",
            "name_suffix": "",
            "institution": "Orlando Regional Medical Center, Department of Emergency Medicine, Orlando, Florida\nUniversity of Central Florida College of Medicine, Department of Emergency Medicine, Orlando, Florida",
            "department": "None"
        },
        {
            "first_name": "Salvatore",
            "middle_name": "",
            "last_name": "Silvestri",
            "name_suffix": "",
            "institution": "Orlando Regional Medical Center, Department of Emergency Medicine, Orlando, Florida\nUniversity of Central Florida College of Medicine, Department of Emergency Medicine, Orlando, Florida",
            "department": "None"
        },
        {
            "first_name": "George",
            "middle_name": "",
            "last_name": "Ralls",
            "name_suffix": "",
            "institution": "Orlando Regional Medical Center, Department of Emergency Medicine, Orlando, Florida",
            "department": "None"
        },
        {
            "first_name": "Amanda",
            "middle_name": "",
            "last_name": "Stone",
            "name_suffix": "",
            "institution": "Orlando Regional Medical Center, Department of Emergency Medicine, Orlando, Florida",
            "department": "None"
        },
        {
            "first_name": "Ayanna",
            "middle_name": "",
            "last_name": "Walker",
            "name_suffix": "",
            "institution": "Orlando Regional Medical Center, Department of Emergency Medicine, Orlando, Florida\nUniversity of Central Florida College of Medicine, Department of Emergency Medicine, Orlando, Florida",
            "department": "None"
        },
        {
            "first_name": "Neal",
            "middle_name": "",
            "last_name": "Mangalat",
            "name_suffix": "",
            "institution": "St Mary’s Hospital, Department of Emergency Medicine, St. Louis, Missouri",
            "department": "None"
        },
        {
            "first_name": "Linda",
            "middle_name": "",
            "last_name": "Papa",
            "name_suffix": "",
            "institution": "Orlando Regional Medical Center, Department of Emergency Medicine, Orlando, Florida\nUniversity of Central Florida College of Medicine, Department of Emergency Medicine, Orlando, Florida",
            "department": "None"
        }
    ],
    "date_submitted": "2017-07-06T21:54:26Z",
    "date_accepted": "2017-07-06T21:54:26Z",
    "date_published": "2018-03-13T19:36:46Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/westjem/article/11058/galley/5956/download/"
        }
    ]
}