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{ "pk": 1106, "title": "Bilateral Cranial Nerve VI Palsies in Cryptococcal Meningitis, HIV, and Syphilis: A Case Report", "subtitle": null, "abstract": "Introduction:\n Cranial nerve (CN) VI palsy is a common complaint seen in the emergency department (ED) and has a wide range of causes. Bilateral CN VI palsies are uncommon and appear to be associated with more severe complications.\nCase Report:\n A 29-year-old male presented to the ED from an ophthalmology office for diplopia, headache, and strabismus. He was found to have bilateral CN VI palsies and new-onset seizure in the ED. A lumbar puncture revealed cryptococcal meningitis. Additional tests revealed a new diagnosis of human immunodeficiency virus (HIV), acquired immunodeficiency syndrome (AIDS), and syphilis.\nConclusion:\n Cryptococcal meningitis remains a life-threatening complication of HIV/AIDS. Coinfections with HIV, particularly syphilis, further complicate a patient’s prognosis as both can lead to devastating neurological sequelae. In cryptococcal meningitis, elevated intracranial pressure is a complication that can manifest as seizures, altered mental status, and cranial nerve palsies.", "language": "en", "license": { "name": "Creative Commons Attribution 4.0", "short_name": "CC BY 4.0", "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.", "url": "https://creativecommons.org/licenses/by/4.0" }, "keywords": [ { "word": "bilateral cranial nerve VI palsies" }, { "word": "cryptococcal meningitis" }, { "word": "HIV/AIDS" }, { "word": "Syphilis" }, { "word": "case report" } ], "section": "ACOEP Case Reports (Invitation Only)", "is_remote": true, "remote_url": "https://escholarship.org/uc/item/9nr7735g", "frozenauthors": [ { "first_name": "Germaine", "middle_name": "", "last_name": "Rival", "name_suffix": "", "institution": "Jefferson Health Northeast, Department of Emergency Medicine, Philadelphia, Pennsylvania", "department": "None" }, { "first_name": "Onyi", "middle_name": "", "last_name": "Okorji", "name_suffix": "", "institution": "Jefferson Health Northeast, Department of Emergency Medicine, Philadelphia, Pennsylvania", "department": "None" }, { "first_name": "Rachael", "middle_name": "", "last_name": "Kern", "name_suffix": "", "institution": "Jefferson Health Northeast, Department of Emergency Medicine, Philadelphia, Pennsylvania", "department": "None" }, { "first_name": "Preya", "middle_name": "", "last_name": "Patel", "name_suffix": "", "institution": "Jefferson Health Northeast, Department of Emergency Medicine, Philadelphia, Pennsylvania", "department": "None" }, { "first_name": "Kate", "middle_name": "", "last_name": "Fradeneck", "name_suffix": "", "institution": "Jefferson Health Northeast, Department of Emergency Medicine, Philadelphia, Pennsylvania", "department": "None" }, { "first_name": "Darragh", "middle_name": "", "last_name": "Cullen", "name_suffix": "", "institution": "Jefferson Health Northeast, Department of Emergency Medicine, Philadelphia, Pennsylvania", "department": "None" } ], "date_submitted": "2021-11-01T23:10:39-07:00", "date_accepted": "2021-11-01T23:10:39-07:00", "date_published": "2021-11-01T23:11:31-07:00", "render_galley": null, "galleys": [ { "label": "", "type": "", "path": "https://journalpub.escholarship.org/uciem_cpcem/article/1106/galley/847/download/" } ] }