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{
    "pk": 15496,
    "title": "Viral Coinfection is Associated with Improved Outcomes in Emergency Department Patients with SARS-CoV-2",
    "subtitle": null,
    "abstract": "Introduction:\n Coinfection with severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) and another virus may influence the clinical trajectory of emergency department (ED) patients. However, little empirical data exists on the clinical outcomes of coinfection with SARS-CoV-2\nMethods:\n In this retrospective cohort analysis, we included adults presenting to the ED with confirmed, symptomatic coronavirus 2019 who also underwent testing for additional viral pathogens within 24 hours. To investigate the association between coinfection status with each of the outcomes, we performed logistic regression.\nResults:\n Of 6,913 ED patients, 5.7% had coinfection. Coinfected individuals were less likely to experience index visit or 30-day hospitalization (odds ratio [OR] 0.57; 95% confidence interval [CI], 0.36-0.90 and OR 0.39; 95% CI, 0.25–0.62, respectively).\nConclusion:\n Coinfection is relatively uncommon in symptomatic ED patients with SARS-CoV-2 and the clinical short- and long-term outcomes are more favorable in coinfected individuals.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "SARS-CoV-2, COVID-19, coinfection, viral testing, hospitalization, emergency department"
        }
    ],
    "section": "Endemic Infections",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/9wv508tr",
    "frozenauthors": [
        {
            "first_name": "Elizabeth",
            "middle_name": "M.",
            "last_name": "Goldberg",
            "name_suffix": "",
            "institution": "Brown University, Department of Emergency Medicine, Providence, Rhode Island",
            "department": "None"
        },
        {
            "first_name": "Kohei",
            "middle_name": "",
            "last_name": "Hasegawa",
            "name_suffix": "",
            "institution": "Massachusetts General Hospital/Harvard Medical School, Department of Emergency Medicine, Boston, Massachusetts",
            "department": "None"
        },
        {
            "first_name": "Alexis",
            "middle_name": "",
            "last_name": "Lawrence",
            "name_suffix": "",
            "institution": "Brown University, Department of Emergency Medicine, Providence, Rhode Island",
            "department": "None"
        },
        {
            "first_name": "Jeffrey",
            "middle_name": "A.",
            "last_name": "Kline",
            "name_suffix": "",
            "institution": "Wayne State University School of Medicine, Department of Emergency Medicine, Detroit, Michigan",
            "department": "None"
        },
        {
            "first_name": "Carlos",
            "middle_name": "A.",
            "last_name": "Camargo, Jr",
            "name_suffix": "",
            "institution": "Massachusetts General Hospital/Harvard Medical School, Department of Emergency Medicine, Boston, Massachusetts",
            "department": "None"
        }
    ],
    "date_submitted": "2021-06-10T13:57:22Z",
    "date_accepted": "2021-06-10T13:57:22Z",
    "date_published": "2021-10-26T19:05:41Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/westjem/article/15496/galley/7802/download/"
        }
    ]
}