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{
    "pk": 15597,
    "title": "Comparing Hepatitis C Virus Screening in Clinics Versus the Emergency Department",
    "subtitle": null,
    "abstract": "Introduction:\n New evidence suggests that emergency department (ED)-based infectious diseases  screening programs have utility. We aimed to compare clinic-based and ED-based hepatitis C virus  (HCV) screening programs within a single health system, to identify key differences in HCV antibody  (Ab) positivity and chronic HCV, as well as population demographics.\nMethods:\n In the clinic-based program, adults in the birth cohort (born 1945-1965) were screened  for HCV. In the ED-based program, non-targeted HCV screening of all adults was conducted. We  included patients screened between June 2019–June 2020. Patients were screened for anti-HCV  Ab, and positive results were followed by HCV viral load (VL) testing. Our primary outcomes were  seroprevalence of HCV Ab and HCV VL.\nResults:\n There were 1,296 and 12,778 patients screened for HCV in the clinics and the ED, respectively.  In the clinic setting, 13 patients (1%) screened positive for HCV Ab and nine (69%) completed VL testing,  which was positive in one patient (11%). In the ED, 1,053 patients (8%) screened positive for HCV Ab  and 847 (80%) underwent reflex VL testing, which was positive in 381 patients (45%). In an ED birth  cohort sub-analysis, Hepatitis C virus Ab seroprevalence was 15% (675/4521).\nConclusion:\n In this study of patients in a single healthcare system, ED-based HCV screening was  higher yield than clinic-based screening.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "hepatitis C virus"
        },
        {
            "word": "emergency department"
        },
        {
            "word": "screening"
        },
        {
            "word": "Public health"
        }
    ],
    "section": "Endemic Infections",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/9r38c53x",
    "frozenauthors": [
        {
            "first_name": "Rebecca",
            "middle_name": "",
            "last_name": "Hluhanich",
            "name_suffix": "",
            "institution": "UC Davis Health, Hepatology and Infectious Diseases Clinical Pharmacy, Sacramento, California",
            "department": "None"
        },
        {
            "first_name": "James",
            "middle_name": "S.",
            "last_name": "Ford",
            "name_suffix": "",
            "institution": "UC Davis Health, Department of Emergency Medicine, Sacramento, California",
            "department": "None"
        },
        {
            "first_name": "Devin",
            "middle_name": "",
            "last_name": "Bruce",
            "name_suffix": "",
            "institution": "UC Davis Health, Department of Emergency Medicine, Sacramento, California",
            "department": "None"
        },
        {
            "first_name": "Tasleem",
            "middle_name": "",
            "last_name": "Chechi",
            "name_suffix": "",
            "institution": "UC Davis Health, Department of Emergency Medicine, Sacramento, California",
            "department": "None"
        },
        {
            "first_name": "Stephanie",
            "middle_name": "",
            "last_name": "Voong",
            "name_suffix": "",
            "institution": "UC Davis Health, Department of Emergency Medicine, Sacramento, California",
            "department": "None"
        },
        {
            "first_name": "Souvik",
            "middle_name": "",
            "last_name": "Sarkar",
            "name_suffix": "",
            "institution": "UC Davis Health, Department of Internal Medicine, Division of Gastroenterology, Sacramento, California",
            "department": "None"
        },
        {
            "first_name": "Patricia",
            "middle_name": "",
            "last_name": "Poole",
            "name_suffix": "",
            "institution": "UC Davis Health, Department of Pharmacy, Sacramento, California",
            "department": "None"
        },
        {
            "first_name": "Nam",
            "middle_name": "",
            "last_name": "Tran",
            "name_suffix": "",
            "institution": "UC Davis Health, Department of Pathology and Laboratory Medicine, Sacramento, California",
            "department": "None"
        },
        {
            "first_name": "Larissa",
            "middle_name": "",
            "last_name": "May",
            "name_suffix": "",
            "institution": "UC Davis Health, Department of Emergency Medicine, Sacramento, California",
            "department": "None"
        }
    ],
    "date_submitted": "2021-06-27T00:27:28Z",
    "date_accepted": "2021-06-27T00:27:28Z",
    "date_published": "2022-03-18T03:25:12Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/westjem/article/15597/galley/7841/download/"
        }
    ]
}