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{
    "pk": 1650,
    "title": "Cardiac Arrest During a Ferric Derisomaltose Infusion Followed by Complete Heart Block: A Case Report",
    "subtitle": null,
    "abstract": "<p><strong>Introduction: </strong>Ferric derisomaltose is the newest available parenteral iron formulation. Studies have demonstrated a good safety profile with improved tolerability compared to alternative parenteral iron formulations. To date there have been no reported acute, life-threatening cardiac events associated with ferric derisomaltose.</p>\n<p><strong>Case Report: </strong>An 86-year-old male who had previously tolerated routine iron infusions received a first dose of ferric derisomaltose at an outpatient infusion clinic. Six minutes into the infusion the patient became unresponsive with no palpable pulse. Return of spontaneous circulation was achieved after two minutes of chest compressions. Electrocardiogram showed complete heart block requiring transcutaneous pacing and vasopressor administration. The patient was transferred to the emergency department for stabilization and then admitted to the cardiac intensive care unit. During admission, the patient received a dual-chamber, permanent pacemaker without complication and was ultimately discharged.</p>\n<p><strong>Conclusion:</strong> It may be reasonable to consider parenteral iron as a toxicological etiology for patients presenting with complete heart block temporally associated with parenteral iron administration, particularly in patients with underlying conduction abnormalities.<br><br></p>\n<p>&nbsp;</p>",
    "language": "eng",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "Ferric compounds"
        },
        {
            "word": "iron"
        },
        {
            "word": "heart block"
        },
        {
            "word": "case report"
        }
    ],
    "section": "Case Reports",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/6vv7r0h2",
    "frozenauthors": [
        {
            "first_name": "Michael",
            "middle_name": "",
            "last_name": "Scott",
            "name_suffix": "",
            "institution": "Beth Israel Deaconess Medical Center, Department of Emergency Medicine, Boston, Massachusetts",
            "department": ""
        },
        {
            "first_name": "Natalie",
            "middle_name": "",
            "last_name": "Jansen",
            "name_suffix": "",
            "institution": "Beth Israel Deaconess Medical Center, Department of Emergency Medicine, Boston, Massachusetts",
            "department": ""
        },
        {
            "first_name": "Leslie",
            "middle_name": "A.",
            "last_name": "Bilello",
            "name_suffix": "",
            "institution": "Beth Israel Deaconess Medical Center, Department of Emergency Medicine, Boston, Massachusetts",
            "department": ""
        }
    ],
    "date_submitted": "2023-09-05T18:44:59.666000Z",
    "date_accepted": "2023-12-30T21:00:41.831000Z",
    "date_published": "2024-04-17T13:00:00Z",
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            "label": "Final Article",
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}