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{
    "pk": 17015,
    "title": "Experiences with Medications for Addiction Treatment Among Emergency Department Patients with Opioid Use Disorder",
    "subtitle": null,
    "abstract": "Introduction: Medications for addiction treatment (MAT) are the evidence-based standard of care for treatment of opioid use disorder (OUD), but stigma continues to surround their use. We conducted an exploratory study to characterize perceptions of different types of MAT among people who use drugs.\nMethods: We conducted this qualitative study in adults with a history of non-medical opioid use who presented to an emergency department for complications of OUD. A semi-structured interview that explored knowledge, perceptions, and attitudes toward MAT was administered, and applied thematic analysis conducted.\nResults: We enrolled 20 adults. All participants had prior experience with MAT. Among participants indicating a preferred treatment modality, buprenorphine was the commonly favored agent. Previous experience with prolonged withdrawal symptoms upon MAT discontinuation and the perception of “trading one drug for another” were common reasons for reluctance to engage in agonist or partial-agonist therapy. While some participants preferred treatment with naltrexone, others were unwilling to initiate antagonist therapy due to fear of precipitated withdrawal. Most participants strongly considered the aversive nature of MAT discontinuation as a barrier to initiating treatment. Participants overall viewed MAT positively, but many had strong preferences for a particular agent.\nConclusion: The anticipation of withdrawal symptoms during initiation and cessation of treatment affected willingness to engage in a specific therapy. Future educational materials for people who use drugs may focus on comparisons of respective benefits and drawbacks of agonists, partial agonists, and antagonists. Emergency clinicians must be prepared to answer questions about MAT discontinuation to effectively engage patients with OUD.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "opioid-related disorders, substance withdrawal, naltrexone, buprenorphine, methadone"
        }
    ],
    "section": "Behavioral Health",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/1db6q7cc",
    "frozenauthors": [
        {
            "first_name": "Charlotte",
            "middle_name": "E.",
            "last_name": "Goldfine",
            "name_suffix": "",
            "institution": "Brigham and Women’s Hospital, Division of Medical Toxicology, Department of Emergency Medicine, Boston, Massachusetts",
            "department": "None"
        },
        {
            "first_name": "Brittany",
            "middle_name": "P.",
            "last_name": "Chapman",
            "name_suffix": "",
            "institution": "University of Massachusetts Chan Medical School, Division of Medical Toxicology, Department of Emergency Medicine, Worcester, Massachusetts",
            "department": "None"
        },
        {
            "first_name": "Melissa",
            "middle_name": "M.",
            "last_name": "Taylor",
            "name_suffix": "",
            "institution": "University of Massachusetts Chan Medical School, Division of Medical Toxicology, Department of Emergency Medicine, Worcester, Massachusetts",
            "department": "None"
        },
        {
            "first_name": "Evan",
            "middle_name": "S.",
            "last_name": "Bradley",
            "name_suffix": "",
            "institution": "University of Massachusetts Chan Medical School, Division of Medical Toxicology, Department of Emergency Medicine, Worcester, Massachusetts",
            "department": "None"
        },
        {
            "first_name": "Stephanie",
            "middle_name": "P.",
            "last_name": "Carreiro",
            "name_suffix": "",
            "institution": "University of Massachusetts Chan Medical School, Division of Medical Toxicology, Department of Emergency Medicine, Worcester, Massachusetts",
            "department": "None"
        },
        {
            "first_name": "Rochelle",
            "middle_name": "R.",
            "last_name": "Rosen",
            "name_suffix": "",
            "institution": "Brown University School of Public Health, Department of Behavioral and Social Sciences, Providence, Rhode Island",
            "department": "None"
        },
        {
            "first_name": "Kavita",
            "middle_name": "M.",
            "last_name": "Babu",
            "name_suffix": "",
            "institution": "University of Massachusetts Chan Medical School, Division of Medical Toxicology, Department of Emergency Medicine, Worcester, Massachusetts",
            "department": "None"
        },
        {
            "first_name": "Jeffrey",
            "middle_name": "T.",
            "last_name": "Lai",
            "name_suffix": "",
            "institution": "University of Massachusetts Chan Medical School, Division of Medical Toxicology, Department of Emergency Medicine, Worcester, Massachusetts",
            "department": "None"
        }
    ],
    "date_submitted": "2022-06-21T02:53:46+02:00",
    "date_accepted": "2022-06-21T02:53:46+02:00",
    "date_published": "2023-02-22T21:58:21+01:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/westjem/article/17015/galley/8604/download/"
        }
    ]
}