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{
    "pk": 17979,
    "title": "Accessibility of Naloxone in Pharmacies Registered Under the Illinois Standing Order",
    "subtitle": null,
    "abstract": "<p><strong>Introduction:</strong> To expand access to naloxone, the state of Illinois implemented a standing order allowing registered pharmacies to dispense the drug without an individual prescription. To participate under the standing order, pharmacies were required to opt in through a formal registration process. In our study we aimed to evaluate the availability and price of naloxone at registered pharmacies.</p>\n<p><strong>Methods:</strong> This was a prospective, de-identified, cross-sectional telephone survey. Trained interviewers posed as potential customers and used a standardized script to determine the availability of naloxone between February–December, 2019. The primary outcome was defined as a pharmacy indicating it carried naloxone, currently had naloxone in stock, and was able to dispense it without an<br>individual prescription.</p>\n<p><strong>Results: </strong>Of 948 registered pharmacies, 886 (93.5%) were successfully contacted. Of those, 792 (83.4%) carried naloxone, 659 (74.4%) had naloxone in stock, and 472 (53.3%) allowed purchase without a prescription. Naloxone nasal spray (86.4%) was the formulation most commonly stocked. Chain pharmacies were more likely to carry naloxone (adjusted odds ratio [aOR] 3.16, 95% confidence interval [CI] 1.97–5.01, P &lt; 0.01) and have naloxone in stock (aOR 2.72, 95% CI 1.76–4.20, P &lt; 0.01), but no more likely to dispense it without a prescription. Pharmacies in higher population areas (aOR 0.99, 95% CI 0.99–0.99, P &lt; 0.05) and rural areas adjacent to metropolitan areas (aOR 0.5, 95% CI 025–0.98, P &lt; 0.05) were less likely to have naloxone available without a prescription. Associations of naloxone availability based on other urbanicity designations, overdose count, and overdose rate were not significant.</p>\n<p><strong>Conclusion: </strong>Among pharmacies in Illinois that formally registered to dispense naloxone without a prescription, the availability of naloxone remains limited. Additional interventions may be needed to maximize the potential impact of a statewide standing order.</p>",
    "language": null,
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "naloxone"
        },
        {
            "word": "Standing order"
        },
        {
            "word": "Opioid"
        },
        {
            "word": "Opiate"
        },
        {
            "word": "emergency department"
        },
        {
            "word": "access"
        }
    ],
    "section": "Behavioral Health",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/9qv0f7tk",
    "frozenauthors": [
        {
            "first_name": "P.",
            "middle_name": "Quincy",
            "last_name": "Moore",
            "name_suffix": "",
            "institution": "Permanente Medical Group, Oakland, California; Kaiser Permanente Oakland Medical Center, Department of Emergency Medicine, Oakland, California",
            "department": "None"
        },
        {
            "first_name": "Kaitlin",
            "middle_name": "",
            "last_name": "Ellis",
            "name_suffix": "",
            "institution": "Brown University, Department of Obstetrics and Gynecology, Providence, Rhode Island",
            "department": "None"
        },
        {
            "first_name": "Patricia",
            "middle_name": "",
            "last_name": "Simmer",
            "name_suffix": "",
            "institution": "University of Chicago, Department of Medicine, Chicago, Illinois",
            "department": "None"
        },
        {
            "first_name": "Mweya",
            "middle_name": "",
            "last_name": "Waetjen",
            "name_suffix": "",
            "institution": "University of Chicago Pritzker, School of Medicine, Chicago, Illinois",
            "department": "None"
        },
        {
            "first_name": "Ellen",
            "middle_name": "",
            "last_name": "Almirol",
            "name_suffix": "",
            "institution": "University of Chicago, Chicago Center for HIV Elimination, Chicago, Illinois",
            "department": "None"
        },
        {
            "first_name": "Elizabeth",
            "middle_name": "",
            "last_name": "Salisbury-Afshar",
            "name_suffix": "",
            "institution": "University of Wisconsin-Madison, School of Medicine and Public Health, Department of Family Medicine and Community Health, Madison, Wisconsin; University of Wisconsin-Madison, School of Medicine and Public Health, Department of Population Health Sciences, Madison, Wisconsin",
            "department": "None"
        },
        {
            "first_name": "Mai",
            "middle_name": "T.",
            "last_name": "Pho",
            "name_suffix": "",
            "institution": "University of Chicago, Department of Medicine, Section of Infectious Diseases and Global Health, Chicago, Illinois",
            "department": "None"
        }
    ],
    "date_submitted": "2023-03-17T08:43:53+11:00",
    "date_accepted": "2023-03-17T08:43:53+11:00",
    "date_published": "2024-05-21T23:00:00+10:00",
    "render_galley": {
        "label": "Final Article",
        "type": "pdf",
        "path": "https://journalpub.escholarship.org/westjem/article/17979/galley/10859/download/"
    },
    "galleys": [
        {
            "label": "Layout",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/westjem/article/17979/galley/10130/download/"
        },
        {
            "label": "Final Article",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/westjem/article/17979/galley/10859/download/"
        }
    ]
}