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{
    "pk": 24822,
    "title": "Voice markers of neuropsychiatric disorders: assessing the generalizability performance of machine learning models",
    "subtitle": null,
    "abstract": "This research explores the potential of machine learning (ML) in identifying vocal markers for schizophrenia. While previous research showed that voice-based ML models can accurately predict schizophrenia diagnosis and symptoms, it is unclear to what extent such ML markers generalize to different clinical subpopulations and languages: the assessment of generalization performance is however crucial for testing their clinical applicability.\nWe systematically examined voice-based ML model performance on a large cross-linguistic dataset (3 languages: Danish, German, Chinese). Employing a rigorous pipeline to minimize overfitting, including cross-validated training sets and multilingual models, we assessed generalization on participants with schizophrenia and controls speaking the same or different languages. Model performance was comparable to state-of-the art findings (F1-score ~ 0.75) within the same language; however, models did not generalize well - showing a substantial decrease - when tested on new languages, and the performance of multilingual models was also generally low (F1-score ~ 0.50).",
    "language": "eng",
    "license": {
        "name": "",
        "short_name": "",
        "text": null,
        "url": ""
    },
    "keywords": [
        {
            "word": "Linguistics; Psychology; Machine learning; Natural Language Processing; Speech recognition"
        }
    ],
    "section": "Abstracts",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/19c9b42w",
    "frozenauthors": [
        {
            "first_name": "Alberto",
            "middle_name": "",
            "last_name": "Parola",
            "name_suffix": "",
            "institution": "Copenhagen University",
            "department": ""
        },
        {
            "first_name": "Astrid",
            "middle_name": "",
            "last_name": "Rybner",
            "name_suffix": "",
            "institution": "Aarhus University",
            "department": ""
        },
        {
            "first_name": "Emil Trenckner",
            "middle_name": "",
            "last_name": "Jessen",
            "name_suffix": "",
            "institution": "Aarhus University",
            "department": ""
        },
        {
            "first_name": "Stine Nyhus",
            "middle_name": "",
            "last_name": "Larsen",
            "name_suffix": "",
            "institution": "Aarhus University",
            "department": ""
        },
        {
            "first_name": "Marie Damsgaard",
            "middle_name": "",
            "last_name": "Mortensen",
            "name_suffix": "",
            "institution": "Aarhus University",
            "department": ""
        },
        {
            "first_name": "Arndis",
            "middle_name": "",
            "last_name": "Simonsen",
            "name_suffix": "",
            "institution": "Aarhus University",
            "department": ""
        },
        {
            "first_name": "Yuan",
            "middle_name": "",
            "last_name": "Zhou",
            "name_suffix": "",
            "institution": "Chinese Academy of Sciences",
            "department": ""
        },
        {
            "first_name": "Katja",
            "middle_name": "",
            "last_name": "Koelkebeck",
            "name_suffix": "",
            "institution": "Hospital and Institute of the University of Duisburg-Essen",
            "department": ""
        },
        {
            "first_name": "Vibeke",
            "middle_name": "",
            "last_name": "Bliksted",
            "name_suffix": "",
            "institution": "Aarhus University",
            "department": ""
        },
        {
            "first_name": "Riccardo",
            "middle_name": "",
            "last_name": "Fusaroli",
            "name_suffix": "",
            "institution": "Aarhus University",
            "department": ""
        }
    ],
    "date_submitted": null,
    "date_accepted": null,
    "date_published": "2024-01-01T11:00:00-07:00",
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}