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{
    "pk": 35556,
    "title": "Smoking-Related Interstitial Lung Disease: CT Image-Based Review and Update",
    "subtitle": null,
    "abstract": "<p>Tobacco smoking is the leading cause of preventable deaths in the United States. Beyond the risks of cardiovascular disease and several cancers, smoking contributes to lung inflammation, lung destruction, and smoking-related interstitial lung diseases (SRILD). SRILD describes a broad range of conditions that includes respiratory bronchiolitis, respiratory bronchiolitis-associated interstitial lung disease, desquamative interstitial pneumonia, pulmonary Langerhans cell histiocytosis, acute eosinophilic pneumonia, idiopathic pulmonary fibrosis, combined pulmonary fibrosis and emphysema, interstitial lung abnormality, and smoking-related interstitial fibrosis.</p>\n<p>Computed tomography (CT) is central to the diagnosis and understanding of clinicopathologic manifestations of smoking-related lung injury. Common features of SRILD on CT include low-attenuation areas, ground-glass opacities, fibrosis, and lung nodules. Although the various SRILDs are often described as distinct entities, they may manifest with nonspecific features or exhibit mixed patterns and may more accurately be described as a continuum of pathology. Understanding the broad range of radiologic features and recognizing the potential coexistence and overlap of disease processes is essential to maintaining an appropriate differential diagnosis. In this article, we review the radiologic findings associated with SRILDs with a focus on diagnostic considerations and challenges when interpreting CT images.</p>",
    "language": null,
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\n\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "Smoking-related interstitial lung disease"
        },
        {
            "word": "interstitial lung disease"
        },
        {
            "word": "emphysema"
        },
        {
            "word": "computed tomography"
        }
    ],
    "section": "Review Article",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/2np382sv",
    "frozenauthors": [
        {
            "first_name": "Justin",
            "middle_name": "J.",
            "last_name": "Sun",
            "name_suffix": "",
            "institution": "David Geffen School of Medicine at UCLA",
            "department": "Department of Radiological Sciences"
        },
        {
            "first_name": "Cameron",
            "middle_name": "",
            "last_name": "Hassani",
            "name_suffix": "",
            "institution": "David Geffen School of Medicine at UCLA",
            "department": "Department of Radiological Sciences"
        },
        {
            "first_name": "Aalok",
            "middle_name": "",
            "last_name": "Shah",
            "name_suffix": "",
            "institution": "David Geffen School of Medicine at UCLA",
            "department": "Department of Radiological Sciences"
        },
        {
            "first_name": "Denise",
            "middle_name": "R.",
            "last_name": "Aberle",
            "name_suffix": "",
            "institution": "David Geffen School of Medicine at UCLA",
            "department": "Department of Radiological Sciences"
        },
        {
            "first_name": "Ashley",
            "middle_name": "E.",
            "last_name": "Prosper",
            "name_suffix": "",
            "institution": "David Geffen School of Medicine at UCLA",
            "department": "Department of Radiological Sciences"
        }
    ],
    "date_submitted": "2023-09-28T14:39:50-07:00",
    "date_accepted": "2023-09-28T14:39:50-07:00",
    "date_published": "2024-11-30T22:05:00-08:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/ucla_rsp/article/35556/galley/30172/download/"
        }
    ]
}