Article Instance

HTTP 200 OK
Allow: GET
Content-Type: application/json
Vary: Accept

{
    "pk": 39703,
    "title": "Case Report: 2-PAM or not 2-PAM",
    "subtitle": null,
    "abstract": "<p><strong>Introduction:</strong> Organophosphates (OP) are used as pest control agents worldwide and have been seen in accidental and intentional poisonings.  </p>\n<p><strong>Case Report:</strong> A patient presented after intentional ingestion of the OP Orthene (50% acephate).  Due to copious secretions, the patient was intubated and given atropine by the paramedic before transport. In the emergency department he displayed both muscarinic and nicotinic effects from OP ingestion. The patient was given multiple doses of atropine and a pralidoxime bolus. He was extubated and transferred to psychiatry two days later. </p>\n<p><strong>Conclusion:</strong> Acute OP exposure is a rare but complex presentation in the United States. In the United States there are bans on several organophosphate varieties, which have reduced the number and severity of OP toxicities. Acephate is generally considered a safer OP by United States regulators and the World Health Organization. In this case report, we describe an OP exposure with marked symptoms requiring intubation and successful treatment with atropine and pralidoxime. We also discuss the role of oximes in acephate toxicity. </p>",
    "language": "eng",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "Orthene"
        },
        {
            "word": "acephate"
        },
        {
            "word": "organophosphate toxicity"
        },
        {
            "word": "Pralidoxime"
        },
        {
            "word": "case report"
        }
    ],
    "section": "Case Reports",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/2t10417b",
    "frozenauthors": [
        {
            "first_name": "Madelyn",
            "middle_name": "",
            "last_name": "Huttner",
            "name_suffix": "",
            "institution": "University of Louisville, School of Medicine Department of Emergency Medicine, Louisville, Kentucky",
            "department": ""
        },
        {
            "first_name": "Kahra",
            "middle_name": "",
            "last_name": "Nix",
            "name_suffix": "",
            "institution": "University of Louisville, School of Medicine Department of Emergency Medicine, Louisville, Kentucky",
            "department": ""
        },
        {
            "first_name": "Caitlyn",
            "middle_name": "",
            "last_name": "Blair",
            "name_suffix": "",
            "institution": "University of Louisville, School of Medicine Department of Emergency Medicine, Louisville, Kentucky",
            "department": ""
        },
        {
            "first_name": "Matthew",
            "middle_name": "",
            "last_name": "Eisenstat",
            "name_suffix": "",
            "institution": "University of Louisville, School of Medicine Department of Emergency Medicine, Louisville, Kentucky",
            "department": ""
        }
    ],
    "date_submitted": "2024-11-07T20:52:33.617000-03:00",
    "date_accepted": "2025-01-17T20:32:25.271000-03:00",
    "date_published": "2025-04-07T12:30:00-04:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "PDF",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/uciem_cpcem/article/39703/galley/35737/download/"
        }
    ]
}