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{
    "pk": 468,
    "title": "Hand Compartment Syndrome Due to N-acetylcysteine Extravasation",
    "subtitle": null,
    "abstract": "N-acetylcysteine (NAC) is the antidote for acetaminophen (APAP)-induced hepatotoxicity. Both intravenous (IV) and oral (PO) NAC formulations are available with equal efficacy. Adverse events from either preparation are rare. We describe a hand compartment syndrome after extravasation of NAC requiring emergent fasciotomy during phase three of treatment for suspected APAP toxicity. Extravasation injuries leading to compartment syndrome are rare. It is unclear whether IV NAC induced a direct tissue toxicinsult, or functioned as a space-occupying lesion to cause a compartment syndrome. Compartment syndrome from extravasation of NAC is possible. In cases where IV access is difficult, PO NAC is analternative.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [],
    "section": "Case Reports",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/0b4897v3",
    "frozenauthors": [
        {
            "first_name": "Joby",
            "middle_name": "",
            "last_name": "Thoppil",
            "name_suffix": "",
            "institution": "Long Island Jewish Medical Center, Northwell Health, New Hyde Park, Department of\nEmergency Medicine, New Hyde Park, New York",
            "department": "None"
        },
        {
            "first_name": "Adam",
            "middle_name": "",
            "last_name": "Berman",
            "name_suffix": "",
            "institution": "Long Island Jewish Medical Center, Northwell Health, New Hyde Park, Department of\nEmergency Medicine, New Hyde Park, New York",
            "department": "None"
        },
        {
            "first_name": "Benjamin",
            "middle_name": "",
            "last_name": "Kessler",
            "name_suffix": "",
            "institution": "Staten Island University Hospital, Northwell Health, Department of Emergency Medicine, Staten Island, New York",
            "department": "None"
        },
        {
            "first_name": "Payal",
            "middle_name": "",
            "last_name": "Sud",
            "name_suffix": "",
            "institution": "Long Island Jewish Medical Center, Northwell Health, New Hyde Park, Department of\nEmergency Medicine, New Hyde Park, New York",
            "department": "None"
        },
        {
            "first_name": "Joshua",
            "middle_name": "",
            "last_name": "Nogar",
            "name_suffix": "",
            "institution": "Long Island Jewish Medical Center, Northwell Health, New Hyde Park, Department of\nEmergency Medicine, New Hyde Park, New York\nNorth Shore University Hospital, Northwell Health, Department of Emergency Medicine, Manhasset, New York",
            "department": "None"
        }
    ],
    "date_submitted": "2017-10-18T19:38:07+02:00",
    "date_accepted": "2017-10-18T19:38:07+02:00",
    "date_published": "2017-10-19T00:05:18+02:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "",
            "path": "https://journalpub.escholarship.org/uciem_cpcem/article/468/galley/232/download/"
        }
    ]
}