Article Instance

HTTP 200 OK
Allow: GET
Content-Type: application/json
Vary: Accept

{
    "pk": 48864,
    "title": "Pleural and Pericardial Effusions Associated with Semaglutide: A Case Report",
    "subtitle": null,
    "abstract": "<p><strong>Introduction</strong>: Semaglutide, a glucagon-like peptide-1 receptor agonist, has gained increasing popularity for managing both type 2 diabetes mellitus and obesity. However, as its use increases, new adverse events are emerging. This case report presents a 70-year-old patient who developed pleural and pericardial effusions likely related to semaglutide use.</p>\n<p><strong>Case Report</strong>: Four weeks after being prescribed semaglutide, a 70-year-old woman presented to the emergency department (ED) with shortness of breath. Diagnostic testing in the ED and hospital revealed that she had both pericardial and exudative pleural effusions, along with a positive anti-nuclear antibody and elevated inflammatory markers. Her signs and symptoms improved with steroid administration, and no other etiology was identified.</p>\n<p><strong>Conclusion</strong>: The patient was diagnosed with drug-induced lupus, likely triggered by semaglutide. This case underscores the importance of recognizing and investigating uncommon drug-related complications. With the growing use of semaglutide, clinicians must remain vigilant for rare adverse effects such as pleural effusions to ensure prompt diagnosis and treatment.</p>",
    "language": "eng",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "Pleural Effusions"
        },
        {
            "word": "Drug Induced Lupus"
        },
        {
            "word": "Semaglutide"
        },
        {
            "word": "case report"
        }
    ],
    "section": "Case Reports",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/2nq2949g",
    "frozenauthors": [
        {
            "first_name": "Maggie",
            "middle_name": "",
            "last_name": "Stark",
            "name_suffix": "",
            "institution": "Brown University, Department of Emergency Medicine, Providence, Rhode Island",
            "department": ""
        },
        {
            "first_name": "Nicholas",
            "middle_name": "",
            "last_name": "Valentini",
            "name_suffix": "",
            "institution": "Brown University, Department of Emergency Medicine, Providence, Rhode Island",
            "department": ""
        }
    ],
    "date_submitted": "2025-07-02T08:23:36.585000-07:00",
    "date_accepted": "2025-10-02T13:52:16.725000-07:00",
    "date_published": "2026-01-22T00:03:00-08:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "PDF",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/uciem_cpcem/article/48864/galley/48096/download/"
        }
    ]
}