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{
    "pk": 49914,
    "title": "Less Than the Sum of its Parts: Complex Models of Cognition Struggle to Capture Regional Activity within Otherwise Well-Fitting Model Structures",
    "subtitle": null,
    "abstract": "Dynamic Causal Modeling is a widely-used method for examining brain connectivity. Most commonly, it is applied to brain regions showing strong responses to experimental tasks, comparing different network configurations based on the temporal dynamics of the neural signals. It can further be applied to models employing a theory-driven selection of brain regions, showing a weaker experimental effect. However, it is unclear if these effects provide sufficient temporal information for Dynamic Causal Modeling to reliably identify the best-fitting model. This study investigated the regional predictive fit in a theory-driven model which has been found to consistently outperform alternatives using Dynamic Causal Modeling. Results revealed issues with the fit of some regions and subjects, raising concerns regarding the reliability of model comparisons using Dynamic Causal Modeling with regions selected based on theory instead of a strong experimental effect.",
    "language": "eng",
    "license": {
        "name": "",
        "short_name": "",
        "text": null,
        "url": ""
    },
    "keywords": [
        {
            "word": "Cognitive Neuroscience; Cognitive architectures; Computational Modeling; Computational neuroscience; fMRI"
        }
    ],
    "section": "Papers with Poster Presentation",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/80b429rx",
    "frozenauthors": [
        {
            "first_name": "Sšnke",
            "middle_name": "",
            "last_name": "Steffen",
            "name_suffix": "",
            "institution": "University of Groningen",
            "department": ""
        },
        {
            "first_name": "Catherine",
            "middle_name": "",
            "last_name": "Sibert",
            "name_suffix": "",
            "institution": "University of Groningen",
            "department": ""
        }
    ],
    "date_submitted": null,
    "date_accepted": null,
    "date_published": "2025-01-01T18:00:00Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "PDF",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/cognitivesciencesociety/article/49914/galley/37876/download/"
        }
    ]
}