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{
    "pk": 49982,
    "title": "Pareto optimality reveals the core computations of the human brain",
    "subtitle": null,
    "abstract": "The human brain supports complex behaviors through diverse functional connectivity patterns. We propose Pareto optimality as a novel framework to understand this functional organization. According to Pareto theory, systems optimizing multiple competing goals do so by balancing trade-offs along a low-dimensional \"Pareto front\" defined by archetypes that each optimize a single goal. Applying Pareto analysis to resting-state fMRI data (HCP, N=1200), we found that individual connectomes lie on a low-dimensional triangle. The three archetypes represent core computational goals: minimizing energetic cost, supporting cognitive control and goal-directed behavior, and enabling internal processing and memory. These goals are reflected in connectivity patterns, network topology, information flow, behavioral and clinical associations. The framework generalizes beyond rest to task-based brain states, and a simple neural model illustrates the trade-offs' computational basis. Pareto optimality offers a principled approach to decompose brain function into core computations across conditions, populations, and stages of life.",
    "language": "eng",
    "license": {
        "name": "",
        "short_name": "",
        "text": null,
        "url": ""
    },
    "keywords": [
        {
            "word": "Cognitive Neuroscience; Cognitive architectures; Computational neuroscience; Dynamic Systems Modeling; fMRI"
        }
    ],
    "section": "Abstracts with Poster Presentation",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/7gn078wm",
    "frozenauthors": [
        {
            "first_name": "Dan",
            "middle_name": "",
            "last_name": "Hilman Amir",
            "name_suffix": "",
            "institution": "The Hebrew University of Jerusalem",
            "department": ""
        },
        {
            "first_name": "Yuval",
            "middle_name": "",
            "last_name": "Hart",
            "name_suffix": "",
            "institution": "The Hebrew University of Jerusalem",
            "department": ""
        }
    ],
    "date_submitted": null,
    "date_accepted": null,
    "date_published": "2025-01-01T19:00:00+01:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "PDF",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/cognitivesciencesociety/article/49982/galley/37944/download/"
        }
    ]
}