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{
    "pk": 558,
    "title": "Anti-factor Xa Monitoring and Activated Charcoal for a Pediatric Patient With Rivaroxaban Overdose",
    "subtitle": null,
    "abstract": "Rivaroxaban, an oral anticoagulant, directly inhibits factor Xa (FXa). A 35-month-old boy was brought to the emergency department 15 minutes after ingesting 200 mg of rivaroxaban (16 mg/kg). Activated charcoal (AC) was administered; the patient was observed with monitoring of plasma anti-FXa levels and discharged the following day after an uneventful hospital observation. We identified two case series and seven case reports of potentially toxic rivaroxaban ingestion in the literature. No serious adverse effects were reported. The present case is the first reported use of anti-FXa monitoring after rivaroxaban ingestion. The magnitude of the effect of AC administration in this patient is unclear.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [],
    "section": "Case Reports",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/0bd0146t",
    "frozenauthors": [
        {
            "first_name": "Brendan",
            "middle_name": "M.",
            "last_name": "Carr",
            "name_suffix": "",
            "institution": "Mayo Clinic, Department of Emergency Medicine, Rochester, Minnesota",
            "department": "None"
        },
        {
            "first_name": "David",
            "middle_name": "J.",
            "last_name": "Roy",
            "name_suffix": "",
            "institution": "Mayo Clinic, Department of Emergency Medicine, Rochester, Minnesota, Mayo Clinic, Pharmacy Services, Rochester, Minnesota",
            "department": "None"
        },
        {
            "first_name": "Stacey",
            "middle_name": "A.",
            "last_name": "Bangh",
            "name_suffix": "",
            "institution": "Hennepin County Medical Center, Minneapolis, Minnesota, Minnesota Poison Control System, Minneapolis, Minnesota",
            "department": "None"
        },
        {
            "first_name": "Thomas",
            "middle_name": "R.",
            "last_name": "Hellmich",
            "name_suffix": "",
            "institution": "Mayo Clinic, Department of Emergency Medicine, Rochester, Minnesota",
            "department": "None"
        },
        {
            "first_name": "Laura",
            "middle_name": "E.",
            "last_name": "Walker",
            "name_suffix": "",
            "institution": "Mayo Clinic, Department of Emergency Medicine, Rochester, Minnesota",
            "department": "None"
        }
    ],
    "date_submitted": "2018-06-05T19:48:41+01:00",
    "date_accepted": "2018-06-05T19:48:41+01:00",
    "date_published": "2018-07-16T20:24:58+01:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "",
            "path": "https://journalpub.escholarship.org/uciem_cpcem/article/558/galley/321/download/"
        }
    ]
}