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{
    "pk": 5763,
    "title": "Inhibition of Successive Positive Contrast in Rats Withdrawn from an Escalating Dose Schedule of D-amphetamine",
    "subtitle": null,
    "abstract": "Rats in a vehicle treated control condition when shifted from 4% to 32% sucrose displayed successive positive contrast by responding at a significantly higher lick rate in a 5 min trial than rats maintained on 32% sucrose throughout the experiment. In contrast, rats treated with an escalating dose regimen of D-amphetamine (1-10 mg/kg) over a 4 day interval failed to display successive positive contrast. Withdrawal from drug treatment had no effect on lick rate or response latency in rats maintained on 32% sucrose. These data are consistent with many previous reports that withdrawal from a binge-like regimen of psychostimulant drug administration disrupts responding for natural reward stimuli. These findings support the use of psychostimulant withdrawal as a model of drug-induced dysphoria and suggest that incentive contrast is a particularly sensitive measure of these changes in motivation and emotion.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "International Journal of Comparative Psychology"
        },
        {
            "word": "Behavior"
        },
        {
            "word": "Behaviour"
        },
        {
            "word": "learning"
        },
        {
            "word": "Behavioral Taxonomy"
        },
        {
            "word": "cognition"
        },
        {
            "word": "Cognitive Processes"
        },
        {
            "word": "Conditioning"
        },
        {
            "word": "inhibition"
        },
        {
            "word": "Successive Positive Contrast"
        },
        {
            "word": "Rat"
        },
        {
            "word": "Sucrose"
        },
        {
            "word": "Emotion"
        },
        {
            "word": "Incentive contrast"
        }
    ],
    "section": "Research Article",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/8f42w3bg",
    "frozenauthors": [
        {
            "first_name": "Giada",
            "middle_name": "",
            "last_name": "Vacca",
            "name_suffix": "",
            "institution": "University of British Columbia, Canada",
            "department": "None"
        },
        {
            "first_name": "Anthony G.",
            "middle_name": "",
            "last_name": "Phillips",
            "name_suffix": "",
            "institution": "University of British Columbia, Canada",
            "department": "None"
        }
    ],
    "date_submitted": "2009-04-30T07:00:00Z",
    "date_accepted": "2009-04-30T07:00:00Z",
    "date_published": "2005-12-31T08:00:00Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "",
            "path": "https://journalpub.escholarship.org/uclapsych_ijcp/article/5763/galley/3518/download/"
        }
    ]
}