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{ "pk": 6550, "title": "Intentional Overdose on Liquid Clonazolam Reversed with Flumazenil: A Case Report", "subtitle": null, "abstract": "<b>Introduction:</b> Clonazolam is a designer benzodiazepine that can be purchased illicitly on the internet. The use of designer benzodiazepines is increasing in both the United States and abroad, and patients may present to the emergency department (ED) after intentional or non-intentional overdose.<br><p><br></p><p><b>Case report: </b>This case report describes a patient who presented to a community ED after an intentional overdose on liquid clonazolam and was successfully treated with flumazenil.</p><p><br></p><p><b>Conclusion: </b>Since the pharmacologic action of clonazolam is similar to benzodiazepines, the sedative-hypnotic effect can be reversed with flumazenil, a benzodiazepine antagonist.</p>", "language": null, "license": { "name": "Creative Commons Attribution 4.0", "short_name": "CC BY 4.0", "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.", "url": "https://creativecommons.org/licenses/by/4.0" }, "keywords": [ { "word": "case report" }, { "word": "clonazolam" }, { "word": "designer benzodiazepine" }, { "word": "flumazenil" } ], "section": "Case Reports", "is_remote": true, "remote_url": "https://escholarship.org/uc/item/5689v3hc", "frozenauthors": [ { "first_name": "Gayle", "middle_name": "", "last_name": "Galletta", "name_suffix": "", "institution": "UMass Chan Medical School, Department of Emergency Medicine, Worcester, Massachusetts", "department": "" } ], "date_submitted": "2023-11-08T13:58:00.260000-05:00", "date_accepted": "2023-11-08T14:00:40.788000-05:00", "date_published": "2023-11-08T09:00:00-05:00", "render_galley": { "label": "Final Article", "type": "pdf", "path": "https://journalpub.escholarship.org/uciem_cpcem/article/6550/galley/3806/download/" }, "galleys": [ { "label": "Final Article", "type": "pdf", "path": "https://journalpub.escholarship.org/uciem_cpcem/article/6550/galley/3806/download/" } ] }