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{
    "pk": 700,
    "title": "Trimethoprim/Sulfamethoxazole-Induced Bradycardia, Renal Failure, AV-Node Blockers, Shock and Hyperkalemia Syndrome",
    "subtitle": null,
    "abstract": "BRASH (bradycardia, renal failure, atrioventricular-node blockers, shock, and hyperkalemia) syndrome is a recently coined term for a condition that describes the severe bradycardia and shock associated with hyperkalemia in patients on atrioventricular (AV)-node blocking agents. The proposed pathophysiology involves a precipitating event that exacerbates renal dysfunction with resulting AV-node blocker and potassium accumulation that act synergistically to precipitate bradycardia and hypotension. This syndrome may be refractory to the usual management of bradycardia. This case describes BRASH syndrome precipitated by trimethoprim/sulfamethoxazole.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [],
    "section": "Case Reports",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/4sw4n693",
    "frozenauthors": [
        {
            "first_name": "Nnaemeka",
            "middle_name": "",
            "last_name": "Diribe",
            "name_suffix": "",
            "institution": "Desert Regional Medical Center, Department of Emergency Medicine, Palm Springs, California",
            "department": "None"
        },
        {
            "first_name": "Jacqueline",
            "middle_name": "",
            "last_name": "Le",
            "name_suffix": "",
            "institution": "Desert Regional Medical Center, Department of Emergency Medicine, Palm Springs, California",
            "department": "None"
        }
    ],
    "date_submitted": "2019-07-19T19:21:32+01:00",
    "date_accepted": "2019-07-19T19:21:32+01:00",
    "date_published": "2019-07-22T20:34:03+01:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "",
            "path": "https://journalpub.escholarship.org/uciem_cpcem/article/700/galley/457/download/"
        }
    ]
}