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{
    "pk": 802,
    "title": "Bowel Perforation in the Emergency Department Related to Bevacizumab Therapy and Recurrent Ovarian Cancer",
    "subtitle": null,
    "abstract": "Case Presentation: We describe the presentation to the emergency department of a patient with recurrent ovarian cancer treated with bevacizumab with the complication of bowel perforation. Discussion: We review the frequency and outcomes of bevacizumab-related bowel perforation. We also report the patient’s imaging findings, including the radiologic presentation of free intraperitoneal air and portal venous gas, both indicative of bowel perforation and the need for emergent surgical evaluation. Our case also illustrates the potentially catastrophic side effects of bevacizumab and other targeted oncologic therapies of which emergecny physicians may not be aware.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "bevacizumab"
        },
        {
            "word": "oncologic emergency"
        },
        {
            "word": "bowel ischemia"
        }
    ],
    "section": "Images in Emergency Medicine",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/71c686bc",
    "frozenauthors": [
        {
            "first_name": "Stuart",
            "middle_name": "A.",
            "last_name": "Ostby",
            "name_suffix": "",
            "institution": "University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Birmingham, Alabama",
            "department": "None"
        },
        {
            "first_name": "Michael",
            "middle_name": "",
            "last_name": "Olushoga",
            "name_suffix": "",
            "institution": "University of Alabama at Birmingham, Department of Emergency Medicine, Birmingham, Alabama",
            "department": "None"
        },
        {
            "first_name": "Charles",
            "middle_name": "A.",
            "last_name": "Leath III",
            "name_suffix": "",
            "institution": "University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Birmingham, Alabama",
            "department": "None"
        },
        {
            "first_name": "Samuel",
            "middle_name": "L.",
            "last_name": "Burleson",
            "name_suffix": "",
            "institution": "University of Alabama at Birmingham, Department of Emergency Medicine, Birmingham, Alabama",
            "department": "None"
        }
    ],
    "date_submitted": "2020-03-27T16:40:00-04:00",
    "date_accepted": "2020-03-27T16:40:00-04:00",
    "date_published": "2020-03-27T16:41:22-04:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "",
            "path": "https://journalpub.escholarship.org/uciem_cpcem/article/802/galley/555/download/"
        }
    ]
}