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{
    "pk": 8033,
    "title": "Does Pre-hospital Endotracheal Intubation Improve Survival in Adults with Non-traumatic Out-of-hospital Cardiac Arrest? A Systematic Review",
    "subtitle": null,
    "abstract": "Introduction: \nEndotracheal intubation (ETI) is currently considered superior to supraglottic airway devices (SGA) for survival and other outcomes among adults with non-traumatic out-of-hospital cardiac arrest (OHCA). We aimed to determine if the research supports this conclusion by conducting a systematic review.\nMethods:\n We searched the MEDLINE, Scopus and CINAHL databases for studies published between January 1, 1980, and 30 April 30, 2013, which compared pre-hospital use of ETI with SGA for outcomes of return of spontaneous circulation (ROSC); survival to hospital admission; survival to hospital discharge; and favorable neurological or functional status. We selected studies using pre-specified criteria. Included studies were independently screened for quality using the Newcastle-Ottawa scale. We did not pool results because of study variability. Study outcomes were extracted and results presented as summed odds ratios with 95% CI.\nResults:\n We identified five eligible studies: one quasi-randomized controlled trial and four cohort studies, involving 303,348 patients in total. Only three of the five studies reported a higher proportion of ROSC with ETI versus SGA with no difference reported in the remaining two. None found significant differences between ETI and SGA for survival to hospital admission or discharge. One study reported better functional status at discharge for ETI versus SGA. Two studies reported no significant difference for favorable neurological status between ETI and SGA.\nConclusion: \nCurrent evidence does not conclusively support the superiority of ETI over SGA for multiple outcomes among adults with OHCA. [West J Emerg Med. 2014;15(7):-0.]",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution-NonCommercial  4.0",
        "short_name": "CC BY-NC 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNonCommercial — You may not use the material for commercial purposes.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by-nc/4.0"
    },
    "keywords": [
        {
            "word": "pre-hospital, emergency medical services, out-of-hospital cardiac arrest, endotracheal intubation, supraglottic airway devices"
        }
    ],
    "section": "Prehospital Care",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/8vv362hm",
    "frozenauthors": [
        {
            "first_name": "Ling",
            "middle_name": "",
            "last_name": "Tiah",
            "name_suffix": "",
            "institution": "Changi General Hospital, Accident and Emergency Department, Singapore",
            "department": "None"
        },
        {
            "first_name": "Kentaro",
            "middle_name": "",
            "last_name": "Kajino",
            "name_suffix": "",
            "institution": "Ministry of Health, Labour and Welfare, Government of Japan, Department of Acute Medicine & Critical Care Medical Center, Osaka National Hospital, Osaka, Japan",
            "department": "None"
        },
        {
            "first_name": "Omer",
            "middle_name": "",
            "last_name": "Alsakaf",
            "name_suffix": "",
            "institution": "Dubai Corporate for Ambulance Services, Dubai, United Arab Emirates",
            "department": "None"
        },
        {
            "first_name": "Dianne Carrol",
            "middle_name": "",
            "last_name": "Tan Bautista",
            "name_suffix": "",
            "institution": "Duke-NUS Graduate Medical School, Center for Quantitative Medicine, Singapore",
            "department": "None"
        },
        {
            "first_name": "Marcus Eng Hock",
            "middle_name": "",
            "last_name": "Ong",
            "name_suffix": "",
            "institution": "Duke-NUS Graduate Medical School, Health Services and Systems Research, Singapore; Singapore General Hospital, Department of Emergency Medicine, Singapore",
            "department": "None"
        },
        {
            "first_name": "Desiree",
            "middle_name": "",
            "last_name": "Lie",
            "name_suffix": "",
            "institution": "Duke-NUS Graduate Medical School, Office of Clinical Sciences, Singapore",
            "department": "None"
        },
        {
            "first_name": "Ghulam Yasin",
            "middle_name": "",
            "last_name": "Naroo",
            "name_suffix": "",
            "institution": "Rashid Hospital, Department of Health & Medical Services, ED-Trauma centre, Dubai, United Arab Emirates",
            "department": "None"
        },
        {
            "first_name": "Nausheen Edwin",
            "middle_name": "",
            "last_name": "Doctor",
            "name_suffix": "",
            "institution": "Singapore General Hospital, Department of Emergency Medicine, Singapore",
            "department": "None"
        },
        {
            "first_name": "Michael",
            "middle_name": "YC",
            "last_name": "Chia",
            "name_suffix": "",
            "institution": "Emergency Department,Tan Tock Seng Hospital, Singapore",
            "department": "None"
        },
        {
            "first_name": "Han Nee",
            "middle_name": "",
            "last_name": "Gan",
            "name_suffix": "",
            "institution": "Changi General Hospital, Accident and Emergency Department, Singapore",
            "department": "None"
        }
    ],
    "date_submitted": "2013-11-13T10:20:14Z",
    "date_accepted": "2013-11-13T10:20:14Z",
    "date_published": "2014-10-28T19:41:19Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/westjem/article/8033/galley/4644/download/"
        }
    ]
}