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{
    "pk": 866,
    "title": "Tranexamic Acid in a Case Report of Life-threatening Nontraumatic Hemorrhage in Immune Thrombocytopenic Purpura",
    "subtitle": null,
    "abstract": "Introduction:\n Immune thrombocytopenic purpura (ITP) is an autoimmune-mediated disorder in which the body produces antibodies that destroy platelets, causing an increased risk of bleeding and bruising. Tranexamic acid (TXA) is a medication that prevents clot breakdown and is used to treat uncontrolled bleeding.\nCase Report:\n We present the case of an 11-year-old female with significant epistaxis and hypotension in the emergency department. Traditional therapies were initiated; however, the patient continued to have bleeding and remained hypotensive, so intravenous TXA was given. The patient’s bleeding then resolved.\nConclusion:\n TXA may be a safe and effective adjunct to traditional therapies for the treatment of life-threatening hemorrhage in ITP patients.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "immune thrombocytopenic purpura"
        },
        {
            "word": "tranexamic acid"
        },
        {
            "word": "epistaxis"
        }
    ],
    "section": "Case Reports",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/3205x12m",
    "frozenauthors": [
        {
            "first_name": "Melanie",
            "middle_name": "M.",
            "last_name": "Randall",
            "name_suffix": "",
            "institution": "Loma Linda University Medical Center and Children’s Hospital, Department of Emergency Medicine, Loma Linda, California",
            "department": "None"
        },
        {
            "first_name": "Jason",
            "middle_name": "",
            "last_name": "Nurse",
            "name_suffix": "",
            "institution": "San Gorgonio Memorial Hospital, Department of Emergency Medicine, Banning, California",
            "department": "None"
        },
        {
            "first_name": "Karan",
            "middle_name": "P.",
            "last_name": "Singh",
            "name_suffix": "",
            "institution": "San Gorgonio Memorial Hospital, Department of Emergency Medicine, Banning, California",
            "department": "None"
        }
    ],
    "date_submitted": "2020-07-10T12:57:06+08:00",
    "date_accepted": "2020-07-10T12:57:06+08:00",
    "date_published": "2020-07-10T12:59:30+08:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "",
            "path": "https://journalpub.escholarship.org/uciem_cpcem/article/866/galley/615/download/"
        }
    ]
}