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{
    "pk": 926,
    "title": "Sequelae of Anticoagulant Therapy in a Patient with History of Pulmonary Malignancy: A Case Report",
    "subtitle": null,
    "abstract": "Introduction:\n In patients with known malignancy and possible intracranial metastatic disease who are receiving treatment with therapeutic anticoagulation, limited data exist regarding risk of intracranial bleeding.\nCase Report:\n We present a case of a 64-year-old female with known lung malignancy, evidence of possible metastatic disease, and bilateral deep vein thrombosis, who suffered severe intracranial hemorrhage following initiation of therapeutic anticoagulation. Current guidelines, available risk- stratification tools, and treatment options with their risks are discussed.\nConclusion:\n In patients with known or suspected intracranial metastatic disease, clinical decision tools can assist both the clinician and the patient in weighing risks and benefits of anticoagulation.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "anticoagulation"
        },
        {
            "word": "malignancy"
        },
        {
            "word": "intracranial hemorrhage"
        },
        {
            "word": "venous thromboembolism"
        },
        {
            "word": "brain metastases"
        }
    ],
    "section": "Case Reports",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/77n2090t",
    "frozenauthors": [
        {
            "first_name": "Christopher",
            "middle_name": "B.",
            "last_name": "Gilsdorf",
            "name_suffix": "",
            "institution": "University of Tennessee Medical Center, Department of Emergency Medicine, Knoxville, Tennessee; University of Tennessee Medical Center, Department of Family Medicine, Knoxville, Tennessee",
            "department": "None"
        },
        {
            "first_name": "Hillary",
            "middle_name": "E.",
            "last_name": "Davis",
            "name_suffix": "",
            "institution": "University of Tennessee Medical Center, Department of Emergency Medicine, Knoxville, Tennessee",
            "department": "None"
        }
    ],
    "date_submitted": "2020-10-05T15:54:40-07:00",
    "date_accepted": "2020-10-05T15:54:40-07:00",
    "date_published": "2020-10-05T15:55:24-07:00",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "",
            "path": "https://journalpub.escholarship.org/uciem_cpcem/article/926/galley/674/download/"
        }
    ]
}