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{
    "pk": 9525,
    "title": "Case Series of Synthetic Cannabinoid Intoxication from One Toxicology Center",
    "subtitle": null,
    "abstract": "Synthetic cannabinoid use has risen at alarming rates. This case series describes 11 patients exposed to the synthetic cannabinoid, MAB-CHMINACA who presented to an emergency department with life-threatening toxicity including obtundation, severe agitation, seizures and death. All patients required sedatives for agitation, nine required endotracheal intubation, three experienced seizures, and one developed hyperthermia. One developed anoxic brain injury, rhabdomyolysis and died. A significant number were pediatric patients. The mainstay of treatment was aggressive sedation and respiratory support. Synthetic cannabinoids pose a major public health risk. Emergency physicians must be aware of their clinical presentation, diagnosis and treatment.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "Synthetic cannabinoids"
        },
        {
            "word": "MAB-CHMINACA toxicity"
        },
        {
            "word": "CB1 CB2 receptor agonism"
        },
        {
            "word": "Schedule 1 Controlled Substance Act"
        },
        {
            "word": "Δ-9 Tetrahydrocannabinol"
        }
    ],
    "section": "Behavioral Health",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/79s5z0wc",
    "frozenauthors": [
        {
            "first_name": "Kenneth",
            "middle_name": "D.",
            "last_name": "Katz",
            "name_suffix": "",
            "institution": "Department of Emergency Medicine, Lehigh Valley Health Network, Allentown, Pennsylvania",
            "department": "None"
        },
        {
            "first_name": "Adam",
            "middle_name": "L.",
            "last_name": "Leonetti",
            "name_suffix": "",
            "institution": "Department of Emergency Medicine, Lehigh Valley Health Network, Allentown, Pennsylvania",
            "department": "None"
        },
        {
            "first_name": "Blake",
            "middle_name": "C.",
            "last_name": "Bailey",
            "name_suffix": "",
            "institution": "Department of Emergency Medicine, Lehigh Valley Health Network, Allentown, Pennsylvania",
            "department": "None"
        },
        {
            "first_name": "Ryan",
            "middle_name": "M.",
            "last_name": "Surmaitis",
            "name_suffix": "",
            "institution": "Department of Emergency Medicine, Lehigh Valley Health Network, Allentown, Pennsylvania",
            "department": "None"
        },
        {
            "first_name": "Eric",
            "middle_name": "R.",
            "last_name": "Eustice",
            "name_suffix": "",
            "institution": "Department of Emergency Medicine, Lehigh Valley Health Network, Allentown, Pennsylvania",
            "department": "None"
        },
        {
            "first_name": "Sherri",
            "middle_name": "",
            "last_name": "Kacinko",
            "name_suffix": "",
            "institution": "NMS Labs, Willow Grove, Pennsylvania",
            "department": "None"
        },
        {
            "first_name": "Scott",
            "middle_name": "M.",
            "last_name": "Wheatley",
            "name_suffix": "",
            "institution": "Pediatric Critical Care, Lehigh Valley Health Network, Allentown, Pennsylvania",
            "department": "None"
        }
    ],
    "date_submitted": "2015-12-17T15:11:49Z",
    "date_accepted": "2015-12-17T15:11:49Z",
    "date_published": "2016-04-26T07:00:00Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/westjem/article/9525/galley/5318/download/"
        }
    ]
}