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{ "pk": 9720, "title": "Risk of Skin and Soft Tissue Infections among Children Found to be Staphylococcus aureus MRSA USA300 Carriers", "subtitle": null, "abstract": "The purpose of this study was to examine community-associated methicillin resistant \nStaphylococcus aureus\n (CA-MRSA) carriage and infections and determine risk factors associated specifically with MRSA USA300. A case control study was conducted in a pediatric emergency department. Nasal and axillary swabs were collected, and participants were interviewed for risk factors.\n \nThe primary outcome was the proportion of \nS. aureus\n carriers among those presenting with and without a skin and soft tissue infection (SSTI). \nS. aureus\n carriers were further categorized into MRSA USA300 carriers or non MRSA USA300 carriers. We found MRSA USA300 carriage rate was higher in children less than 2 years of age, those with an SSTI, children with recent antibiotic use, and those with a family history of SSTI. MRSA USA300 carriers were also more likely to have lower income compared to non MRSA USA300 carriers and no \nS. aureus\n carriers. Rates of PVL genes were higher in MRSA carriage isolates with an SSTI, compared to MRSA carriage isolates of patients without an SSTI with an association between MRSA USA300 carriage and presence of PVL in those diagnosed with an abscess.", "language": "en", "license": { "name": "Creative Commons Attribution 4.0", "short_name": "CC BY 4.0", "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.", "url": "https://creativecommons.org/licenses/by/4.0" }, "keywords": [ { "word": "Staphylococcus aureus carriage" }, { "word": "MRSA" }, { "word": "Children" }, { "word": "Skin and Soft tissue infection" } ], "section": "Endemic Infections", "is_remote": true, "remote_url": "https://escholarship.org/uc/item/4zn7k35w", "frozenauthors": [ { "first_name": "Lilly", "middle_name": "", "last_name": "Immergluck", "name_suffix": "", "institution": "Morehouse School of Medicine", "department": "None" }, { "first_name": "Shabnam", "middle_name": "", "last_name": "Jain", "name_suffix": "", "institution": "Emory University", "department": "None" }, { "first_name": "Susan", "middle_name": "", "last_name": "Ray", "name_suffix": "", "institution": "Emory University", "department": "None" }, { "first_name": "Robert", "middle_name": "", "last_name": "Mayberry", "name_suffix": "", "institution": "Morehouse School of Meddicine", "department": "None" }, { "first_name": "Sarah", "middle_name": "", "last_name": "Satola", "name_suffix": "", "institution": "Emory University", "department": "None" }, { "first_name": "Trisha", "middle_name": "Chan", "last_name": "Parker", "name_suffix": "", "institution": "Postraduate Medical Institute", "department": "None" }, { "first_name": "Keming", "middle_name": "", "last_name": "Yuan", "name_suffix": "", "institution": "Morehouse School of Medicine", "department": "None" }, { "first_name": "Anaam", "middle_name": "", "last_name": "Mohammed", "name_suffix": "", "institution": "Pediatric Emergency Medicine Associates", "department": "None" }, { "first_name": "Robert", "middle_name": "C", "last_name": "Jerris", "name_suffix": "", "institution": "Emory University", "department": "None" } ], "date_submitted": "2016-03-28T16:15:27Z", "date_accepted": "2016-03-28T16:15:27Z", "date_published": "2017-01-28T00:25:01Z", "render_galley": null, "galleys": [ { "label": "", "type": "pdf", "path": "https://journalpub.escholarship.org/westjem/article/9720/galley/5384/download/" } ] }