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{
    "pk": 9730,
    "title": "Two Cases of Anti-NMDA Receptor Encephalitis",
    "subtitle": null,
    "abstract": "Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a form of autoimmune encephalitis with prominent neuropsychiatric features. Patients present with acute psychosis, memory impairment, dyskinesias, seizures, and/or speech disorders. The clinical course is often complicated by respiratory failure, requiring intubation. Approximately half of patients are found to have an associated ovarian tumor, which expresses NMDAR (Tuzun). Recognition of anti-NMDAR encephalitis by emergency physicians is essential in order to initiate early treatment and avoid psychiatric misdiagnosis. The disease is highly treatable with tumor removal and immunosuppression, and most patients demonstrate a full recovery. In this case series, we report two cases of anti-NMDAR encephalitis in adult women in the United States and provide a review of the literature.",
    "language": "en",
    "license": {
        "name": "Creative Commons Attribution 4.0",
        "short_name": "CC BY 4.0",
        "text": "Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.\r\n\r\nNo additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.",
        "url": "https://creativecommons.org/licenses/by/4.0"
    },
    "keywords": [
        {
            "word": "anti-NMDA receptor encephalitis"
        },
        {
            "word": "viral encephalitis"
        },
        {
            "word": "paraneoplastic encephalitis"
        },
        {
            "word": "Autoimmune encephalitis"
        }
    ],
    "section": "Diagnostic Acumen",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/0q38f6fr",
    "frozenauthors": [
        {
            "first_name": "Jessa",
            "middle_name": "",
            "last_name": "Baker, BA",
            "name_suffix": "",
            "institution": "University of California, Irvine School of Medicine, Irvine, California",
            "department": "None"
        },
        {
            "first_name": "Chris",
            "middle_name": "",
            "last_name": "Jeziorkowski, MD",
            "name_suffix": "",
            "institution": "Advocate Christ Medical Center, Department of Emergency Medicine, Oak Lawn, Illinois",
            "department": "None"
        },
        {
            "first_name": "Cory",
            "middle_name": "",
            "last_name": "Siebe, MD",
            "name_suffix": "",
            "institution": "Denver Health Medical Center, Department of Emergency Medicine, Denver, Colorado",
            "department": "None"
        },
        {
            "first_name": "Megan",
            "middle_name": "B.",
            "last_name": "Osborn, MD, MHPE",
            "name_suffix": "",
            "institution": "University of California, Irvine School of Medicine, Department of Emergency Medicine, Irvine, California",
            "department": "None"
        }
    ],
    "date_submitted": "2016-04-13T07:05:15Z",
    "date_accepted": "2016-04-13T07:05:15Z",
    "date_published": "2016-07-21T18:46:14Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/westjem/article/9730/galley/5388/download/"
        }
    ]
}