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{
    "pk": 16616,
    "title": "Fatal Metformin Overdose Presenting with Progressive Hyperglycemia",
    "subtitle": null,
    "abstract": "A 29-year-old man with no history of diabetes ingested over 60 grams of metformin in a suicide attempt. He presented to the emergency department with acute renal insufficiency, severe lactic acidosis, and rapidly-progressive hyperglycemia. The patient’s peak serum glucose level of 707 mg/dL is the highest yet reported in a case of metformin toxicity. Treatment included sodium bicarbonate infusion and hemodialysis, but the patient suffered several cardiac arrests with pulseless electrical activity and ultimately expired 25 hours after the ingestion.\n\n\n[WestJEM. 2008;9:160-164.]",
    "language": "en",
    "license": {
        "name": "none",
        "short_name": "none",
        "text": "",
        "url": "http://google.com"
    },
    "keywords": [
        {
            "word": "overdose"
        },
        {
            "word": "poisoning"
        },
        {
            "word": "Metformin"
        },
        {
            "word": "hyperglycemia"
        },
        {
            "word": "lactic acidosis"
        }
    ],
    "section": "Article",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/1nh2f6wn",
    "frozenauthors": [
        {
            "first_name": "Jeffrey",
            "middle_name": "R",
            "last_name": "Suchard",
            "name_suffix": "",
            "institution": "Department of Emergency Medicine, University of California, Irvine School of Medicine",
            "department": "None"
        },
        {
            "first_name": "Thomas",
            "middle_name": "A",
            "last_name": "Grotsky",
            "name_suffix": "",
            "institution": "Department of Emergency Medicine, University of California, Irvine School of Medicine",
            "department": "None"
        }
    ],
    "date_submitted": "2008-02-19T08:00:00Z",
    "date_accepted": "2008-02-19T08:00:00Z",
    "date_published": "2008-06-23T07:00:00Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/westjem/article/16616/galley/8407/download/"
        }
    ]
}