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{ "pk": 17126, "title": "Lidocaine Toxicity Misinterpreted as a Stroke", "subtitle": null, "abstract": "For more than 50 years lidocaine has been used to treat ventricular arrhythmias. Neurologic dysfunction, manifested as a stroke, occurred acutely in an 87-year-old woman after she had been administered repeated doses of lidocaine, a lidocaine infusion, then an intravenous amiodarone infusion for ventricular tachycardia. This was ultimately diagnosed as lidocaine toxicity with a serum lidocaine level of 7.9 mg/L (1.5 - 6.0 mg/L). We discuss lidocaine toxicity and risk factors leading to its development, which include particularly hepatic dysfunction, cardiac dysfunction, advanced age and other drug administration.\n\n\n[West J Emerg Med. 2009;10(4):292-294.]", "language": "en", "license": { "name": "none", "short_name": "none", "text": "", "url": "http://google.com" }, "keywords": [ { "word": "Lidocaine" }, { "word": "drug toxicity" }, { "word": "stroke" }, { "word": "Emergency Medicine" } ], "section": "Article", "is_remote": true, "remote_url": "https://escholarship.org/uc/item/6b31j01f", "frozenauthors": [ { "first_name": "Benjamin", "middle_name": "", "last_name": "Bursell", "name_suffix": "", "institution": "University of CT Combined Residency in EM", "department": "None" }, { "first_name": "Alan", "middle_name": "J", "last_name": "Smally", "name_suffix": "", "institution": "University of Connecticut School of Medicine and Dentistry", "department": "None" }, { "first_name": "Richard", "middle_name": "M", "last_name": "Ratzan", "name_suffix": "", "institution": "University of CT School of Medicine and Dentistry", "department": "None" } ], "date_submitted": "2008-05-25T00:00:00-07:00", "date_accepted": "2008-05-25T00:00:00-07:00", "date_published": "2009-11-01T00:00:00-07:00", "render_galley": null, "galleys": [ { "label": "", "type": "pdf", "path": "https://journalpub.escholarship.org/westjem/article/17126/galley/8652/download/" } ] }