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{
    "pk": 28989,
    "title": "The role of AMPA receptor exchange in systems memory reconsolidation: Acomputational model",
    "subtitle": null,
    "abstract": "In the mammalian brain, a newly acquired memory depends on the hippocampus for maintenance and recall, but over timethe neocortex takes over these functions, rendering the memory hippocampus-independent. The process responsible forthis transformation is called systems memory consolidation. Interestingly, retrieval of a well-consolidated memory cantrigger a temporary return to a hippocampus-dependent state, a phenomenon known as systems memory reconsolidation.The neural mechanisms underlying systems memory consolidation and reconsolidation are not well understood. Here,we propose a neural model based on well-documented mechanisms of synaptic plasticity and stability and describe acomputational implementation that demonstrates the models ability to account for a range of findings from the systemsconsolidation and reconsolidation literature. Based on the computational model, we derive a number of predictions andsuggest experiments that may put them to the test.",
    "language": "eng",
    "license": {
        "name": "",
        "short_name": "",
        "text": null,
        "url": ""
    },
    "keywords": [],
    "section": "Poster Presentations with Abstracts",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/00s7m48t",
    "frozenauthors": [
        {
            "first_name": "Peter",
            "middle_name": "",
            "last_name": "Helfer",
            "name_suffix": "",
            "institution": "McGill University",
            "department": ""
        },
        {
            "first_name": "Thomas",
            "middle_name": "",
            "last_name": "Shultz",
            "name_suffix": "",
            "institution": "McGill University",
            "department": ""
        }
    ],
    "date_submitted": null,
    "date_accepted": null,
    "date_published": "2019-01-01T18:00:00Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "PDF",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/cognitivesciencesociety/article/28989/galley/18860/download/"
        }
    ]
}