Article Instance

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{
    "pk": 30037,
    "title": "Applying the Common Model of Cognition to Resting-State fMRI Leads to theIdentification of Abnormal Functional Connectivity in Parkinson’s Disease",
    "subtitle": null,
    "abstract": "A complete understanding of cognitive function in humansmust incorporate a model of interactions between networkedbrain regions. Alterations to these network interactions under-lie cognitive impairment in many neurodegenerative diseases,providing an important physiological link between brain struc-ture and cognitive function. Cognitive architectures have of-ten been used to explain how healthy brains function, typi-cally using task-based activity. However, this description isincomplete. Most systems-level brain activity is spontaneous,or intrinsic, and occurs whether or not a subject is performinga task. Here, we provide evidence that the Common Modelof Cognition, a consensus model derived from an analysis ofexisting cognitive architectures, can (a) be generalized to ac-count for brain activity at rest, rather than during tasks, and (b)correctly identify differences in basal ganglia connectivity inParkinson’s Disease.",
    "language": "eng",
    "license": {
        "name": "",
        "short_name": "",
        "text": null,
        "url": ""
    },
    "keywords": [
        {
            "word": "Common Model of Cognition; Resting-statefMRI; Parkinson’s Disease; Dynamic Causal Modeling"
        }
    ],
    "section": "Poster Session 3",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/3404d4c0",
    "frozenauthors": [
        {
            "first_name": "Micah",
            "middle_name": "",
            "last_name": "Ketola",
            "name_suffix": "",
            "institution": "University of Washington",
            "department": ""
        },
        {
            "first_name": "Shelby",
            "middle_name": "",
            "last_name": "Thompson",
            "name_suffix": "",
            "institution": "Spelman College",
            "department": ""
        },
        {
            "first_name": "Tara",
            "middle_name": "",
            "last_name": "Madhyastha",
            "name_suffix": "",
            "institution": "Amazon Web Services",
            "department": ""
        },
        {
            "first_name": "Thomas",
            "middle_name": "J.",
            "last_name": "Grabowski",
            "name_suffix": "",
            "institution": "University of Washington",
            "department": ""
        },
        {
            "first_name": "Andrea",
            "middle_name": "",
            "last_name": "Stocco",
            "name_suffix": "",
            "institution": "University of Washington",
            "department": ""
        }
    ],
    "date_submitted": null,
    "date_accepted": null,
    "date_published": "2020-01-01T18:00:00Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "PDF",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/cognitivesciencesociety/article/30037/galley/19891/download/"
        }
    ]
}