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{
    "pk": 50146,
    "title": "SIESTA: A Spectral-Temporal Unified Framework for Robust Cross-Subject EEG Analysis",
    "subtitle": null,
    "abstract": "Electroencephalography (EEG) provides critical insights into brain activity, yet its inherent variability and nonstationary nature pose significant challenges for computational analysis, particularly in cross-subject generalization tasks. We present SIESTA (Spectral Invariant EEG-based Semi-causal Transform Architecture), a novel EEG foundation model that addresses these challenges through three key innovations: (1) VQGAN-based spectral tokenization capturing wavelet representation of EEG; (2) a dual-stream Transformer architecture pre-trained using a semi-causal generative modeling approach; and (3) Contrastive Invariant Fine-Tuning (CIFT), a label-free domain adaptation strategy that aligns feature distributions across subjects by integrating spectral-temporal dynamics. Pre-trained on over 32,900 hours of diverse EEG data, SIESTA achieves state-of-the-art performance in epilepsy monitoring, improves F1-score by $12.4 \\%$ on scalp EEG and $8.7 \\%$ on intracranial EEG, respectively. Beyond epilepsy, SIESTA demonstrates strong generalizability to non-epilepsy tasks, including motor imagery and sleep stage classification. These results validate that spectrotemporal integration and domain-invariant learning are fundamental for modeling cross-subject EEG variability, establishing new benchmarks for robust brain-computing systems.",
    "language": "eng",
    "license": {
        "name": "",
        "short_name": "",
        "text": null,
        "url": ""
    },
    "keywords": [
        {
            "word": "Artificial Intelligence; Pattern recognition; Big data; Electroencephalography (EEG); Neural Networks"
        }
    ],
    "section": "Abstracts with Poster Presentation (accepted as Abstracts)",
    "is_remote": true,
    "remote_url": "https://escholarship.org/uc/item/9nb9z2pw",
    "frozenauthors": [
        {
            "first_name": "Ruizhe",
            "middle_name": "",
            "last_name": "Zheng",
            "name_suffix": "",
            "institution": "Fudan University",
            "department": ""
        },
        {
            "first_name": "Yuguo",
            "middle_name": "",
            "last_name": "Yu",
            "name_suffix": "",
            "institution": "Fudan University",
            "department": ""
        }
    ],
    "date_submitted": null,
    "date_accepted": null,
    "date_published": "2025-01-01T18:00:00Z",
    "render_galley": null,
    "galleys": [
        {
            "label": "PDF",
            "type": "pdf",
            "path": "https://journalpub.escholarship.org/cognitivesciencesociety/article/50146/galley/38108/download/"
        }
    ]
}