Preprints
Filtering by Subject: Pharmacology, Toxicology and Environmental Health
The environmental impact of a malaria clinical trial in Mali: Life cycle assessment reveals high emissions due to international travel and local electricity use and identifies opportunities for sustainable improvement
Published: 2024-09-14
Subjects: Pharmacology, Toxicology and Environmental Health
Climate change may be the single largest threat facing humanity and ecosystems, necessitating decarbonization across all sectors, including healthcare and academia. With the aim of informing and supporting sustainable research practices, we performed a life cycle assessment of a clinical trial conducted in Mali. The trial involved 80 malaria-infected participants in Ouélessébougou who were [...]
A Community-Centric Intelligent Cyberinfrastructure for Addressing Nitrogen Pollution using Web Systems and Conversational AI
Published: 2024-09-13
Subjects: Agricultural Science, Agriculture, Environmental Studies, Marine Biology, Pharmacology, Toxicology and Environmental Health
The Blue-Green Action Platform (BlueGAP) information system (IS) is an intelligent cyberinfrastructure framework designed to support large-scale water quality assessments in the context of demographic statistics and community stories about water issues. The system prioritizes collaboration with interested parties in three pilot watersheds with test cases implemented in US locations including [...]
Elevated Methane in Massachusetts and Rhode Island Homes Using Fracked Gas
Published: 2024-09-11
Subjects: Environmental Sciences, Pharmacology, Toxicology and Environmental Health, Public Health
We surveyed 197 Massachusetts and Rhode Island houses ranging in building style and age to test whether homes served by fracked gas have higher indoor methane concentrations ([CH4]) than in homes without gas. The answer is clearly “Yes”. From basements and single-floor slab homes to third floors of triple deckers, indoor [CH4] in households with gas service was significantly elevated over outdoor [...]
Recovering nutrients from urine – a golden opportunity for sustainable fertiliser production
Published: 2024-08-29
Subjects: Agricultural Science, Bioresource and Agricultural Engineering, Environmental Studies, Pharmacology, Toxicology and Environmental Health
The utilization of nitrogen (N) and phosphorus (P) in agriculture has surpassed the safe-operating thresholds for biogeochemical cycles, necessitating the adoption of more efficient nutrient management strategies to restore this balance. The predominant source of N and P supplementation globally stems from the application of synthetic fertilizers. This study explores the potential of nutrient [...]
Transforming place-based management within watersheds in Fiji: the Watershed Interventions for Systems Health project
Published: 2023-02-08
Subjects: Pharmacology, Toxicology and Environmental Health
Watersheds offer opportunities for place-based interventions to transform systems health via preventative versus reactive approaches to management that achieve multiple co-benefits for public and environmental health. The Watershed Interventions for Systems Health in Fiji (WISH Fiji) project embraced participatory knowledge co-production and action-oriented research to identify risks to public [...]
Use of geochemical and ecotoxicological approaches to evaluate sediment quality in differentially-contaminated, legally protected reserves along the coast of São Paulo State, Brazil
Published: 2020-08-19
Subjects: Life Sciences, Pharmacology, Toxicology and Environmental Health, Toxicology
We compared sediment quality in estuaries at three locations along the coast of São Paulo State, Brazil, using geochemical analyses and whole sediment toxicity tests, performed during the southern winter and summer of 2013. Each locality is afforded a different degree of legal protection, and shows a distinct level of pollution: overall, Rio Diana (RD, most polluted, Permanent Protection Area) [...]